Reactome: A Curated Pathway Database
All 5 results
Pathways (2) Reactions (1) Proteins (1) Others (1)
Protein: UniProt:Q92908 GATA6 (Homo sapiens)
Last changed: 2015-03-10 08:59:22

Pathway: Hemostasis (Homo sapiens)
Hemostasis is a physiological response that culminates in the arrest of bleeding from an injured vessel. Under normal conditions the vascular endothelium supports vasodilation, inhibits platelet adhesion and activation, suppresses coagulation, enhances fibrin cleavage and is anti-inflammatory in character. Under acute vascular trauma, vasoconstrictor mechanisms predominate and the endothelium becomes p
Last changed: 2015-03-06 23:15:47

Pathway: Factors involved in megakaryocyte development and platelet production (Homo sapiens)
Megakaryocytes (MKs) give rise to circulating platelets (thrombocytes) through terminal differentiation of MKs which release cytoplasmic fragments as circulating platelets. As MKs mature they undergo endoreduplication (polyploidisation) and expansion of cytoplasmic mass to cell sizes larger than 50-100 microns, and ploidy ranges up to 128 N. As MK's mature, the polyploid nucleus becomes horseshoe-shap
Last changed: 2015-03-06 23:15:47

Reaction: ZFPM proteins bind GATA proteins (Homo sapiens)
The Friend of GATA (FOG) family of proteins are a highly-conserved family of large multitype zinc finger cofactors that bind to the amino zinc finger of GATA transcription factors, modulating their activity. GATA proteins are named for the DNA consensus sequence they recognize, (T/A)GATA(A/G). FOG/GATA protein interactions are essential for the development of many tissues. All six GATA family members a
Last changed: 2015-03-06 10:40:16

Complex: ZFPM proteins:GATA proteins [nucleoplasm] (Homo sapiens)
ZFPM proteins:GATA proteins
Last changed: 2010-11-08 15:26:41