Reactome: A Curated Pathway Database
All 6 results
Pathways (4) Reactions (1) Proteins (1) Others (0)
Protein: UniProt:Q9NQ40 SLC52A3 (Homo sapiens)
Last changed: 2015-03-10 08:59:22

Pathway: Metabolism (Homo sapiens)
Metabolic processes in human cells generate energy through the oxidation of molecules consumed in the diet and mediate the synthesis of diverse essential molecules not taken in the diet as well as the inactivation and elimination of toxic ones generated endogenously or present in the extracellular environment. The processes of energy metabolism can be classified into two groups according to whether the
Last changed: 2015-03-06 23:15:47

Pathway: Metabolism of vitamins and cofactors (Homo sapiens)
Vitamins are a diverse group of organic compounds, required in small amounts in the diet. They have distinct biochemical roles, often as coenzymes, and are either not synthesized or synthesized only in limited amounts by human cells. Vitamins are classified according to their solubility, either fat-soluble or water-soluble. The physiological processes dependent on vitamin-requiring reactions include ma
Last changed: 2015-03-06 23:15:47

Pathway: Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Vitamins are a diverse group of organic compounds, required in small amounts in the diet. They have distinct biochemical roles, often as coenzymes, and are either not synthesized or synthesized only in limited amounts by human cells. Vitamins are classified according to their solubility, either fat-soluble or water-soluble. The physiological processes dependent on vitamin-requiring reactions include ma
Last changed: 2015-03-06 23:15:47

Pathway: Vitamin B2 (riboflavin) metabolism (Homo sapiens)
Riboflavin (vitamin B2, E101) is an essential component for the cofactors FAD (flavin-adenine dinucleotide) and FMN (flavin mononucleotide). Together with NAD+ and NADP+, FAD and FMN are important hydrogen carriers and take part in more than 100 redox reactions involved in energy metabolism. Riboflavin is present in many vegetables and meat and during digestion, various flavoproteins from food are degr
Last changed: 2015-03-06 23:15:47

Reaction: SLC52A3 transports extracellular RIB to cytosol (Homo sapiens)
Solute carrier family 52, riboflavin transporter, member 3 (SLC52A3) transports riboflavin (RIB) from the lumen into small intestine epithelial cells (Yao et al. 2010). Activity is inhibited by riboflavin analogues such as flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) (Yao et al. 2010). Defects in SLC52A3 cause Brown-Vialetto-Van Laere syndrome type 1 (BVVLS1; MIM:211530). BVVLS1 is
Last changed: 2015-03-12 13:50:51