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What is Reactome ?
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Table of Contents
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How do I search ?
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Species
Homo sapiens (75275)
Mus musculus (50800)
Danio rerio (46786)
Rattus norvegicus (43779)
Bos taurus (42556)
Sus scrofa (40353)
Canis familiaris (39362)
Xenopus tropicalis (38674)
Gallus gallus (37792)
Drosophila melanogaster (32808)
Caenorhabditis elegans (29154)
Dictyostelium discoideum (18444)
Saccharomyces cerevisiae (11390)
Schizosaccharomyces pombe (10009)
Entries without species (7756)
Plasmodium falciparum (7035)
Severe acute respiratory syndrome coronavirus 2 (665)
Human immunodeficiency virus 1 (634)
Human SARS coronavirus (551)
Influenza A virus (471)
Mycobacterium tuberculosis (360)
Human cytomegalovirus (353)
Clostridium botulinum (172)
Xenopus laevis (149)
Oryctolagus cuniculus (140)
Hepatitis C Virus (130)
Rotavirus (118)
Escherichia coli (97)
Human herpesvirus 1 (86)
Human respiratory syncytial virus A (80)
Infectious bronchitis virus (71)
Hepatitis B virus (65)
Measles virus (64)
Salmonella typhimurium (61)
Bacillus anthracis (57)
Neisseria meningitidis serogroup B (57)
Cricetulus griseus (56)
Chlamydia trachomatis (54)
Listeria monocytogenes (46)
Leishmania major (41)
Clostridium tetani (31)
Neisseria gonorrhoeae (28)
Ovis aries (26)
Vaccinia virus (26)
Corynephage beta (25)
Meleagris gallopavo (24)
Staphylococcus aureus (22)
Cavia porcellus (21)
Human gammaherpesvirus 4 (19)
Human herpesvirus 8 (19)
Cercopithecus aethiops (18)
Human alphaherpesvirus 2 (18)
Hepatitis C virus genotype 2a (13)
Dengue virus (12)
West Nile virus (11)
Macaca mulatta (10)
Candida albicans (7)
Human papillomavirus type 16 (7)
Mycobacterium tuberculosis H37Rv (7)
Tick-borne encephalitis virus (7)
Clostridium perfringens (6)
Sindbis virus (5)
Arenicola marina (4)
Cowpox virus (4)
Leishmania mexicana (4)
Sendai virus (4)
Triticum aestivum (4)
Vigna radiata var. radiata (4)
Alphapapillomavirus 9 (3)
Chlorocebus sabaeus (3)
Hepatitis C virus subtype 1a (3)
Homarus americanus (3)
Legionella pneumophila (3)
Molluscum contagiosum virus subtype 1 (3)
Penicillium chrysogenum (3)
Rotavirus A (3)
Crithidia fasciculata (2)
Felis catus (2)
Listeria monocytogenes serotype 1/2a (1)
Toxoplasma gondii (1)
Types
Protein (244184)
Complex (103856)
Reaction (91543)
Set (45314)
Pathway (22221)
Interactor (8624)
Genes and Transcripts (5888)
Chemical Compound (3685)
Icon (2253)
DNA Sequence (1635)
Polymer (1505)
Drug (1119)
Person (908)
RNA Sequence (627)
OtherEntity (347)
Compartments
cytosol (152831)
plasma membrane (110734)
nucleoplasm (96171)
extracellular region (59024)
endoplasmic reticulum membrane (17755)
endoplasmic reticulum lumen (14779)
mitochondrial matrix (10912)
Golgi membrane (10812)
Golgi lumen (9949)
mitochondrial inner membrane (6282)
mitochondrial outer membrane (4370)
lysosomal lumen (4055)
endosome membrane (3407)
lysosomal membrane (3343)
nuclear envelope (2261)
secretory granule lumen (2199)
trans-Golgi network membrane (2065)
peroxisomal matrix (2059)
ficolin-1-rich granule lumen (1986)
clathrin-coated endocytic vesicle membrane (1810)
early endosome membrane (1674)
secretory granule membrane (1671)
endocytic vesicle membrane (1620)
ER to Golgi transport vesicle membrane (1566)
azurophil granule lumen (1496)
endoplasmic reticulum-Golgi intermediate compartment membrane (1464)
phagocytic vesicle membrane (1456)
specific granule membrane (1405)
peroxisomal membrane (1394)
platelet alpha granule lumen (1208)
integral component of lumenal side of endoplasmic reticulum membrane (1165)
tertiary granule membrane (1128)
transport vesicle (1115)
ficolin-1-rich granule membrane (1081)
recycling endosome membrane (1046)
azurophil granule membrane (1039)
cilium (1010)
mitochondrial intermembrane space (934)
specific granule lumen (913)
tertiary granule lumen (898)
cytoplasmic vesicle membrane (894)
photoreceptor disc membrane (842)
ciliary tip (708)
transport vesicle membrane (457)
ciliary membrane (455)
chromosome (451)
endocytic vesicle lumen (439)
endosome lumen (437)
chromosome, centromeric region (422)
cell junction (420)
COPII-coated ER to Golgi transport vesicle (401)
ciliary base (390)
axonemal microtubule (382)
lipid droplet (346)
multivesicular body lumen (339)
phagocytic vesicle lumen (331)
Golgi-associated vesicle membrane (330)
endolysosome membrane (300)
melanosome membrane (274)
smooth endoplasmic reticulum (249)
platelet dense granule lumen (245)
extracellular exosome (233)
phagophore assembly site membrane (224)
late endosome membrane (221)
platelet alpha granule membrane (214)
cornified envelope (205)
cytoplasm (204)
platelet dense tubular network membrane (199)
synaptic vesicle membrane (198)
clathrin-coated endocytic vesicle (196)
autophagosome membrane (195)
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane (188)
phagocytic vesicle (187)
clathrin-sculpted monoamine transport vesicle membrane (177)
endosome (170)
sarcoplasmic reticulum membrane (170)
cytoplasmic side of plasma membrane (149)
early endosome (144)
lamellar body (141)
peptidoglycan-based cell wall (139)
double membrane vesicle viral factory outer membrane (133)
nucleolus (124)
external side of plasma membrane (120)
photoreceptor outer segment membrane (119)
platelet dense granule membrane (113)
endoplasmic reticulum quality control compartment (109)
clathrin-sculpted glutamate transport vesicle membrane (86)
melanosome lumen (85)
microtubule organizing center (84)
mitochondrion (74)
viral envelope (73)
endoplasmic reticulum-Golgi intermediate compartment (72)
phagolysosome (72)
lamellar body membrane (70)
basolateral plasma membrane (69)
early endosome lumen (68)
integral component of cytoplasmic side of endoplasmic reticulum membrane (62)
endolysosome lumen (61)
apical plasma membrane (58)
late endosome lumen (54)
Reaction types
binds (18992)
phosphorylates (5202)
transports (2237)
translocates (1778)
transfers (1678)
lyses (1622)
hydrolyses (1595)
ubiquitinates (1393)
cleaves (1114)
activates (954)
oxidises (933)
reduces (660)
regulates (579)
exchanges (541)
dephosphorylates (536)
hydroxylates (484)
deubiquitinates (446)
dehydrogenates (333)
transforms (330)
hydrates (222)
ligates (211)
demethylates (167)
synthesizes (159)
decarboxylates (156)
isomerises (148)
inhibits (137)
deaminates (131)
converts (125)
deacetylates (121)
transaminates (115)
dehydrates (100)
signals (98)
co-transports (77)
condenses (67)
dioxygenates (61)
elongates (46)
extends (45)
desaturates (31)
sulfates (28)
initiates (26)
inserts (20)
ribosylates (19)
combines (4)
unwinds (2)
dismutates (1)
Filtering Parameters
Species
Homo sapiens (75275)
Mus musculus (50800)
Danio rerio (46786)
Rattus norvegicus (43779)
Bos taurus (42556)
Sus scrofa (40353)
Canis familiaris (39362)
Xenopus tropicalis (38674)
Gallus gallus (37792)
Drosophila melanogaster (32808)
Caenorhabditis elegans (29154)
Dictyostelium discoideum (18444)
Saccharomyces cerevisiae (11390)
Schizosaccharomyces pombe (10009)
Entries without species (7756)
Plasmodium falciparum (7035)
Severe acute respiratory syndrome coronavirus 2 (665)
Human immunodeficiency virus 1 (634)
Human SARS coronavirus (551)
Influenza A virus (471)
Mycobacterium tuberculosis (360)
Human cytomegalovirus (353)
Clostridium botulinum (172)
Xenopus laevis (149)
Oryctolagus cuniculus (140)
Hepatitis C Virus (130)
Rotavirus (118)
Escherichia coli (97)
Human herpesvirus 1 (86)
Human respiratory syncytial virus A (80)
Infectious bronchitis virus (71)
Hepatitis B virus (65)
Measles virus (64)
Salmonella typhimurium (61)
Bacillus anthracis (57)
Neisseria meningitidis serogroup B (57)
Cricetulus griseus (56)
Chlamydia trachomatis (54)
Listeria monocytogenes (46)
Leishmania major (41)
Clostridium tetani (31)
Neisseria gonorrhoeae (28)
Ovis aries (26)
Vaccinia virus (26)
Corynephage beta (25)
Meleagris gallopavo (24)
Staphylococcus aureus (22)
Cavia porcellus (21)
Human gammaherpesvirus 4 (19)
Human herpesvirus 8 (19)
Cercopithecus aethiops (18)
Human alphaherpesvirus 2 (18)
Hepatitis C virus genotype 2a (13)
Dengue virus (12)
West Nile virus (11)
Macaca mulatta (10)
Candida albicans (7)
Human papillomavirus type 16 (7)
Mycobacterium tuberculosis H37Rv (7)
Tick-borne encephalitis virus (7)
Clostridium perfringens (6)
Sindbis virus (5)
Arenicola marina (4)
Cowpox virus (4)
Leishmania mexicana (4)
Sendai virus (4)
Triticum aestivum (4)
Vigna radiata var. radiata (4)
Alphapapillomavirus 9 (3)
Chlorocebus sabaeus (3)
Hepatitis C virus subtype 1a (3)
Homarus americanus (3)
Legionella pneumophila (3)
Molluscum contagiosum virus subtype 1 (3)
Penicillium chrysogenum (3)
Rotavirus A (3)
Crithidia fasciculata (2)
Felis catus (2)
Listeria monocytogenes serotype 1/2a (1)
Toxoplasma gondii (1)
Types
Protein (244184)
Complex (103856)
Reaction (91543)
Set (45314)
Pathway (22221)
Interactor (8624)
Genes and Transcripts (5888)
Chemical Compound (3685)
Icon (2253)
DNA Sequence (1635)
Polymer (1505)
Drug (1119)
Person (908)
RNA Sequence (627)
OtherEntity (347)
Compartments
cytosol (152831)
plasma membrane (110734)
nucleoplasm (96171)
extracellular region (59024)
endoplasmic reticulum membrane (17755)
endoplasmic reticulum lumen (14779)
mitochondrial matrix (10912)
Golgi membrane (10812)
Golgi lumen (9949)
mitochondrial inner membrane (6282)
mitochondrial outer membrane (4370)
lysosomal lumen (4055)
endosome membrane (3407)
lysosomal membrane (3343)
nuclear envelope (2261)
secretory granule lumen (2199)
trans-Golgi network membrane (2065)
peroxisomal matrix (2059)
ficolin-1-rich granule lumen (1986)
clathrin-coated endocytic vesicle membrane (1810)
early endosome membrane (1674)
secretory granule membrane (1671)
endocytic vesicle membrane (1620)
ER to Golgi transport vesicle membrane (1566)
azurophil granule lumen (1496)
endoplasmic reticulum-Golgi intermediate compartment membrane (1464)
phagocytic vesicle membrane (1456)
specific granule membrane (1405)
peroxisomal membrane (1394)
platelet alpha granule lumen (1208)
integral component of lumenal side of endoplasmic reticulum membrane (1165)
tertiary granule membrane (1128)
transport vesicle (1115)
ficolin-1-rich granule membrane (1081)
recycling endosome membrane (1046)
azurophil granule membrane (1039)
cilium (1010)
mitochondrial intermembrane space (934)
specific granule lumen (913)
tertiary granule lumen (898)
cytoplasmic vesicle membrane (894)
photoreceptor disc membrane (842)
ciliary tip (708)
transport vesicle membrane (457)
ciliary membrane (455)
chromosome (451)
endocytic vesicle lumen (439)
endosome lumen (437)
chromosome, centromeric region (422)
cell junction (420)
COPII-coated ER to Golgi transport vesicle (401)
ciliary base (390)
axonemal microtubule (382)
lipid droplet (346)
multivesicular body lumen (339)
phagocytic vesicle lumen (331)
Golgi-associated vesicle membrane (330)
endolysosome membrane (300)
melanosome membrane (274)
smooth endoplasmic reticulum (249)
platelet dense granule lumen (245)
extracellular exosome (233)
phagophore assembly site membrane (224)
late endosome membrane (221)
platelet alpha granule membrane (214)
cornified envelope (205)
cytoplasm (204)
platelet dense tubular network membrane (199)
synaptic vesicle membrane (198)
clathrin-coated endocytic vesicle (196)
autophagosome membrane (195)
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane (188)
phagocytic vesicle (187)
clathrin-sculpted monoamine transport vesicle membrane (177)
endosome (170)
sarcoplasmic reticulum membrane (170)
cytoplasmic side of plasma membrane (149)
early endosome (144)
lamellar body (141)
peptidoglycan-based cell wall (139)
double membrane vesicle viral factory outer membrane (133)
nucleolus (124)
external side of plasma membrane (120)
photoreceptor outer segment membrane (119)
platelet dense granule membrane (113)
endoplasmic reticulum quality control compartment (109)
clathrin-sculpted glutamate transport vesicle membrane (86)
melanosome lumen (85)
microtubule organizing center (84)
mitochondrion (74)
viral envelope (73)
endoplasmic reticulum-Golgi intermediate compartment (72)
phagolysosome (72)
lamellar body membrane (70)
basolateral plasma membrane (69)
early endosome lumen (68)
integral component of cytoplasmic side of endoplasmic reticulum membrane (62)
endolysosome lumen (61)
apical plasma membrane (58)
late endosome lumen (54)
Reaction types
binds (18992)
phosphorylates (5202)
transports (2237)
translocates (1778)
transfers (1678)
lyses (1622)
hydrolyses (1595)
ubiquitinates (1393)
cleaves (1114)
activates (954)
oxidises (933)
reduces (660)
regulates (579)
exchanges (541)
dephosphorylates (536)
hydroxylates (484)
deubiquitinates (446)
dehydrogenates (333)
transforms (330)
hydrates (222)
ligates (211)
demethylates (167)
synthesizes (159)
decarboxylates (156)
isomerises (148)
inhibits (137)
deaminates (131)
converts (125)
deacetylates (121)
transaminates (115)
dehydrates (100)
signals (98)
co-transports (77)
condenses (67)
dioxygenates (61)
elongates (46)
extends (45)
desaturates (31)
sulfates (28)
initiates (26)
inserts (20)
ribosylates (19)
combines (4)
unwinds (2)
dismutates (1)
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