Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
Advanced search
This parser supports full
Lucene QueryParser syntax
including:
Quotation marks for exact searches and brackets for grouping terms together
Boolean operators: 'AND', 'OR', 'NOT', '+' and '-'
Wildcard operators: '?' and '*'
Proximity matching: "raf map"~4 searches for raf and map within 4 words from each other
(raf AND map) OR (name:"PTEN S170N") OR (apoptosis) OR stID:"REACT_12858.1" OR stID:"R-HSA-198344.1"
Filtering Parameters
×
Species
Homo sapiens (72209)
Mus musculus (49067)
Danio rerio (46799)
Rattus norvegicus (43017)
Sus scrofa (35735)
Canis familiaris (34997)
Xenopus tropicalis (34414)
Gallus gallus (34080)
Drosophila melanogaster (30795)
Caenorhabditis elegans (26931)
Bos taurus (24117)
Dictyostelium discoideum (22895)
Saccharomyces cerevisiae (13182)
Schizosaccharomyces pombe (11842)
Entries without species (6785)
Plasmodium falciparum (6105)
Human immunodeficiency virus 1 (625)
Influenza A virus (468)
Human SARS coronavirus (447)
Severe acute respiratory syndrome coronavirus 2 (420)
Mycobacterium tuberculosis (360)
Human cytomegalovirus (349)
Clostridium botulinum (172)
Xenopus laevis (147)
Oryctolagus cuniculus (139)
Hepatitis C Virus (127)
Rotavirus (115)
Escherichia coli (98)
Human herpesvirus 1 (86)
Infectious bronchitis virus (71)
Measles virus (63)
Hepatitis B virus (61)
Bacillus anthracis (57)
Neisseria meningitidis serogroup B (57)
Cricetulus griseus (56)
Chlamydia trachomatis (54)
Salmonella typhimurium (53)
Listeria monocytogenes (46)
Leishmania major (41)
Clostridium tetani (31)
Neisseria gonorrhoeae (28)
Vaccinia virus (26)
Corynephage beta (25)
Meleagris gallopavo (24)
Cavia porcellus (21)
Human gammaherpesvirus 4 (19)
Human herpesvirus 8 (19)
Staphylococcus aureus (19)
Cercopithecus aethiops (18)
Human alphaherpesvirus 2 (17)
Dengue virus (13)
Hepatitis C virus genotype 2a (13)
Hepatitis C virus subtype 1a (13)
Ovis aries (13)
West Nile virus (11)
Macaca mulatta (10)
Mycobacterium tuberculosis H37Rv (8)
Candida albicans (7)
Human papillomavirus type 16 (7)
Tick-borne encephalitis virus (7)
Clostridium perfringens (6)
Respiratory syncytial virus (6)
Sindbis virus (5)
Arenicola marina (4)
Cowpox virus (4)
Leishmania mexicana (4)
Sendai virus (4)
Triticum aestivum (4)
Vigna radiata var. radiata (4)
Alphapapillomavirus 9 (3)
Chlorocebus sabaeus (3)
Homarus americanus (3)
Legionella pneumophila (3)
Molluscum contagiosum virus subtype 1 (3)
Penicillium chrysogenum (3)
Rotavirus A (3)
Crithidia fasciculata (2)
Felis catus (2)
Listeria monocytogenes serotype 1/2a (1)
Toxoplasma gondii (1)
Types
Protein (232127)
Complex (93279)
Reaction (80644)
Set (42212)
Pathway (21244)
Interactor (8524)
Genes and Transcripts (6224)
Chemical Compound (3541)
Icon (2040)
Polymer (1443)
DNA Sequence (1075)
Person (870)
RNA Sequence (510)
ChemicalDrug (495)
OtherEntity (338)
ProteinDrug (39)
Compartments
cytosol (139368)
plasma membrane (101242)
nucleoplasm (89369)
extracellular region (54353)
endoplasmic reticulum membrane (16228)
endoplasmic reticulum lumen (13640)
Golgi membrane (10554)
mitochondrial matrix (9995)
Golgi lumen (9368)
mitochondrial inner membrane (5862)
mitochondrial outer membrane (3800)
lysosomal lumen (3318)
endosome membrane (3204)
lysosomal membrane (3142)
nuclear envelope (2015)
peroxisomal matrix (1999)
early endosome membrane (1954)
secretory granule lumen (1937)
trans-Golgi network membrane (1896)
ER to Golgi transport vesicle membrane (1854)
ficolin-1-rich granule lumen (1819)
endocytic vesicle membrane (1685)
clathrin-coated endocytic vesicle membrane (1676)
phagocytic vesicle membrane (1665)
secretory granule membrane (1600)
integral component of lumenal side of endoplasmic reticulum membrane (1445)
azurophil granule lumen (1414)
endoplasmic reticulum-Golgi intermediate compartment membrane (1371)
peroxisomal membrane (1300)
recycling endosome membrane (1168)
specific granule membrane (1155)
tertiary granule membrane (1049)
platelet alpha granule lumen (1025)
ficolin-1-rich granule membrane (1011)
transport vesicle (983)
azurophil granule membrane (955)
cilium (945)
mitochondrial intermembrane space (926)
photoreceptor disc membrane (810)
specific granule lumen (807)
tertiary granule lumen (803)
cytoplasmic vesicle membrane (791)
ciliary tip (674)
transport vesicle membrane (479)
endocytic vesicle lumen (421)
chromosome (408)
ciliary membrane (401)
COPII-coated ER to Golgi transport vesicle (393)
chromosome, centromeric region (385)
cell junction (378)
multivesicular body lumen (369)
axonemal microtubule (365)
phagocytic vesicle lumen (315)
ciliary base (314)
endosome lumen (310)
Golgi-associated vesicle membrane (291)
endolysosome membrane (278)
lipid droplet (259)
melanosome membrane (247)
platelet dense granule lumen (246)
smooth endoplasmic reticulum (246)
extracellular exosome (230)
phagophore assembly site membrane (211)
endosome (208)
late endosome membrane (203)
cytoplasm (197)
platelet alpha granule membrane (194)
synaptic vesicle membrane (190)
autophagosome membrane (184)
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane (178)
clathrin-sculpted monoamine transport vesicle membrane (171)
clathrin-coated endocytic vesicle (167)
platelet dense tubular network membrane (167)
cornified envelope (162)
phagocytic vesicle (147)
sarcoplasmic reticulum membrane (140)
cell wall (139)
lamellar body (136)
cytoplasmic side of plasma membrane (130)
early endosome (118)
photoreceptor outer segment membrane (116)
host cell cytosol (114)
nucleolus (113)
double membrane vesicle viral factory outer membrane (106)
endoplasmic reticulum quality control compartment (106)
platelet dense granule membrane (98)
external side of plasma membrane (91)
clathrin-sculpted glutamate transport vesicle membrane (84)
phagolysosome (77)
microtubule organizing center (76)
melanosome lumen (74)
viral envelope (73)
endolysosome lumen (71)
mitochondrion (70)
endoplasmic reticulum-Golgi intermediate compartment (63)
integral component of cytoplasmic side of endoplasmic reticulum membrane (61)
early endosome lumen (58)
late endosome lumen (54)
lamellar body membrane (53)
recycling endosome (46)
Reaction types
binds (15722)
phosphorylates (4570)
transports (1886)
translocates (1614)
lyses (1556)
hydrolyses (1530)
transfers (1512)
ubiquitinates (1149)
cleaves (1010)
activates (877)
oxidises (862)
reduces (610)
regulates (551)
dephosphorylates (439)
exchanges (437)
deubiquitinates (412)
hydroxylates (392)
dehydrogenates (311)
transforms (272)
hydrates (213)
ligates (185)
demethylates (167)
synthesizes (153)
decarboxylates (147)
isomerises (141)
deacetylates (132)
deaminates (127)
inhibits (126)
converts (116)
dehydrates (100)
signals (84)
transaminates (82)
co-transports (74)
condenses (64)
dioxygenates (57)
elongates (43)
extends (43)
desaturates (28)
sulfates (28)
initiates (24)
inserts (20)
ribosylates (20)
combines (4)
dismutates (1)
Filtering Parameters
Species
Homo sapiens (72209)
Mus musculus (49067)
Danio rerio (46799)
Rattus norvegicus (43017)
Sus scrofa (35735)
Canis familiaris (34997)
Xenopus tropicalis (34414)
Gallus gallus (34080)
Drosophila melanogaster (30795)
Caenorhabditis elegans (26931)
Bos taurus (24117)
Dictyostelium discoideum (22895)
Saccharomyces cerevisiae (13182)
Schizosaccharomyces pombe (11842)
Entries without species (6785)
Plasmodium falciparum (6105)
Human immunodeficiency virus 1 (625)
Influenza A virus (468)
Human SARS coronavirus (447)
Severe acute respiratory syndrome coronavirus 2 (420)
Mycobacterium tuberculosis (360)
Human cytomegalovirus (349)
Clostridium botulinum (172)
Xenopus laevis (147)
Oryctolagus cuniculus (139)
Hepatitis C Virus (127)
Rotavirus (115)
Escherichia coli (98)
Human herpesvirus 1 (86)
Infectious bronchitis virus (71)
Measles virus (63)
Hepatitis B virus (61)
Bacillus anthracis (57)
Neisseria meningitidis serogroup B (57)
Cricetulus griseus (56)
Chlamydia trachomatis (54)
Salmonella typhimurium (53)
Listeria monocytogenes (46)
Leishmania major (41)
Clostridium tetani (31)
Neisseria gonorrhoeae (28)
Vaccinia virus (26)
Corynephage beta (25)
Meleagris gallopavo (24)
Cavia porcellus (21)
Human gammaherpesvirus 4 (19)
Human herpesvirus 8 (19)
Staphylococcus aureus (19)
Cercopithecus aethiops (18)
Human alphaherpesvirus 2 (17)
Dengue virus (13)
Hepatitis C virus genotype 2a (13)
Hepatitis C virus subtype 1a (13)
Ovis aries (13)
West Nile virus (11)
Macaca mulatta (10)
Mycobacterium tuberculosis H37Rv (8)
Candida albicans (7)
Human papillomavirus type 16 (7)
Tick-borne encephalitis virus (7)
Clostridium perfringens (6)
Respiratory syncytial virus (6)
Sindbis virus (5)
Arenicola marina (4)
Cowpox virus (4)
Leishmania mexicana (4)
Sendai virus (4)
Triticum aestivum (4)
Vigna radiata var. radiata (4)
Alphapapillomavirus 9 (3)
Chlorocebus sabaeus (3)
Homarus americanus (3)
Legionella pneumophila (3)
Molluscum contagiosum virus subtype 1 (3)
Penicillium chrysogenum (3)
Rotavirus A (3)
Crithidia fasciculata (2)
Felis catus (2)
Listeria monocytogenes serotype 1/2a (1)
Toxoplasma gondii (1)
Types
Protein (232127)
Complex (93279)
Reaction (80644)
Set (42212)
Pathway (21244)
Interactor (8524)
Genes and Transcripts (6224)
Chemical Compound (3541)
Icon (2040)
Polymer (1443)
DNA Sequence (1075)
Person (870)
RNA Sequence (510)
ChemicalDrug (495)
OtherEntity (338)
ProteinDrug (39)
Compartments
cytosol (139368)
plasma membrane (101242)
nucleoplasm (89369)
extracellular region (54353)
endoplasmic reticulum membrane (16228)
endoplasmic reticulum lumen (13640)
Golgi membrane (10554)
mitochondrial matrix (9995)
Golgi lumen (9368)
mitochondrial inner membrane (5862)
mitochondrial outer membrane (3800)
lysosomal lumen (3318)
endosome membrane (3204)
lysosomal membrane (3142)
nuclear envelope (2015)
peroxisomal matrix (1999)
early endosome membrane (1954)
secretory granule lumen (1937)
trans-Golgi network membrane (1896)
ER to Golgi transport vesicle membrane (1854)
ficolin-1-rich granule lumen (1819)
endocytic vesicle membrane (1685)
clathrin-coated endocytic vesicle membrane (1676)
phagocytic vesicle membrane (1665)
secretory granule membrane (1600)
integral component of lumenal side of endoplasmic reticulum membrane (1445)
azurophil granule lumen (1414)
endoplasmic reticulum-Golgi intermediate compartment membrane (1371)
peroxisomal membrane (1300)
recycling endosome membrane (1168)
specific granule membrane (1155)
tertiary granule membrane (1049)
platelet alpha granule lumen (1025)
ficolin-1-rich granule membrane (1011)
transport vesicle (983)
azurophil granule membrane (955)
cilium (945)
mitochondrial intermembrane space (926)
photoreceptor disc membrane (810)
specific granule lumen (807)
tertiary granule lumen (803)
cytoplasmic vesicle membrane (791)
ciliary tip (674)
transport vesicle membrane (479)
endocytic vesicle lumen (421)
chromosome (408)
ciliary membrane (401)
COPII-coated ER to Golgi transport vesicle (393)
chromosome, centromeric region (385)
cell junction (378)
multivesicular body lumen (369)
axonemal microtubule (365)
phagocytic vesicle lumen (315)
ciliary base (314)
endosome lumen (310)
Golgi-associated vesicle membrane (291)
endolysosome membrane (278)
lipid droplet (259)
melanosome membrane (247)
platelet dense granule lumen (246)
smooth endoplasmic reticulum (246)
extracellular exosome (230)
phagophore assembly site membrane (211)
endosome (208)
late endosome membrane (203)
cytoplasm (197)
platelet alpha granule membrane (194)
synaptic vesicle membrane (190)
autophagosome membrane (184)
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane (178)
clathrin-sculpted monoamine transport vesicle membrane (171)
clathrin-coated endocytic vesicle (167)
platelet dense tubular network membrane (167)
cornified envelope (162)
phagocytic vesicle (147)
sarcoplasmic reticulum membrane (140)
cell wall (139)
lamellar body (136)
cytoplasmic side of plasma membrane (130)
early endosome (118)
photoreceptor outer segment membrane (116)
host cell cytosol (114)
nucleolus (113)
double membrane vesicle viral factory outer membrane (106)
endoplasmic reticulum quality control compartment (106)
platelet dense granule membrane (98)
external side of plasma membrane (91)
clathrin-sculpted glutamate transport vesicle membrane (84)
phagolysosome (77)
microtubule organizing center (76)
melanosome lumen (74)
viral envelope (73)
endolysosome lumen (71)
mitochondrion (70)
endoplasmic reticulum-Golgi intermediate compartment (63)
integral component of cytoplasmic side of endoplasmic reticulum membrane (61)
early endosome lumen (58)
late endosome lumen (54)
lamellar body membrane (53)
recycling endosome (46)
Reaction types
binds (15722)
phosphorylates (4570)
transports (1886)
translocates (1614)
lyses (1556)
hydrolyses (1530)
transfers (1512)
ubiquitinates (1149)
cleaves (1010)
activates (877)
oxidises (862)
reduces (610)
regulates (551)
dephosphorylates (439)
exchanges (437)
deubiquitinates (412)
hydroxylates (392)
dehydrogenates (311)
transforms (272)
hydrates (213)
ligates (185)
demethylates (167)
synthesizes (153)
decarboxylates (147)
isomerises (141)
deacetylates (132)
deaminates (127)
inhibits (126)
converts (116)
dehydrates (100)
signals (84)
transaminates (82)
co-transports (74)
condenses (64)
dioxygenates (57)
elongates (43)
extends (43)
desaturates (28)
sulfates (28)
initiates (24)
inserts (20)
ribosylates (20)
combines (4)
dismutates (1)
© 2021
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
