Reactome: A Curated Pathway Database

Expression of IFNG-stimulated genes

Stable Identifier
R-HSA-1031716
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

IFN-gamma stimulates gene expression of about 200 genes which include the primary response genes like IRFs, Fc-gamma receptor (FCGR), GBPs (guanylate-binding proteins) and also major histocompatibility complex (MHC) class I and class II molecules, proteins involved in antigen presentation, antiviral proteins like PKR, OAS proteins etc. A wonderful list of most of the IFN-gamma inducible proteins with corresponding literature are mentioned in the review article and the supplementary document by Boehm et al 1997.

Literature References
Participants
Participant Of
This entity is regulated by:
Orthologous Events