Reactome: A Curated Pathway Database
Attention
The EBI data centre will be shutting down from the afternoon (BST) of Friday 26th August until the afternoon of Tuesday 30th August 2016 for essential maintenance. This might have an impact on some Reactome services and we apologize for any inconvenience.

IL6:sIL6R binds to JAKs:IL6RB (gp130)

Stable Identifier
R-HSA-1067651
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The complex of IL6 and the soluble, short form of the IL6 receptor binds to surface expressed IL6RB (gp130), a process known as trans signaling (Rose-John et al. 2006).

Literature References
Participants
Participant Of
This entity is regulated by:
Orthologous Events