Reactome: A Curated Pathway Database

IL6:sIL6R binds to JAKs:IL6RB (gp130) (R-HSA-1067651) [Homo sapiens]


The complex of IL6 and the soluble, short form of the IL6 receptor binds to surface expressed IL6RB (gp130), a process known as trans signaling (Rose-John et al. 2006).

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Compartment extracellular region , plasma membrane
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