Reactome: A Curated Pathway Database

Interleukin-6 binds to IL-6 receptor alpha subunit (R-HSA-1067667) [Homo sapiens]


Interleukin-6 site I interacts with the non-sigaling but ligand specific IL-6R alpha chain.

Additional Information
Compartment plasma membrane , extracellular region
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Literature References
pubMedId Title Journal Year
2788034 Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130 Cell 1989