Reactome: A Curated Pathway Database

PDPK1 phosphorylates AKT2 (R-HSA-109702) [Homo sapiens]


Two specific sites in AKT2, one in the kinase domain (Thr-309) and the other in the C-terminal regulatory region (Ser-474), need to be phosphorylated for its full activation.

Additional Information
Compartment cytosol , plasma membrane
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
PDPK1:PIP3 protein serine/threonine kinase activity (0004674)