Reactome: A Curated Pathway Database

p-S259,S621-RAF1

Stable Identifier
R-HSA-109786
Type
Protein
Species
Homo sapiens
Compartment
Synonyms
RAF proto-oncogene serine/threonine-protein kinase , Raf-1, C-RAF, cRaf
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
RAF1, RAF
Chain
chain:1-648
Reference Genes
Reference Transcript
Other Identifiers
 11716472_a_at  11748273_a_at  16950848  1917_at  1C1Y
 1FAQ  1FAR  1GUA  1RFA  201244_s_at
 38742_s_at  38743_f_at  3CU8  3IQJ  3IQU
 3IQV  3KUC  3KUD  3NKX  3O8I
 3OMV  4FJ3  4G0N  4G3X  4IEA
 4IHL  5894  8085374  A_23_P40952  CAB019291
 CCDS2612  ENSG00000132155  ENSP00000251849  ENSP00000401888  ENST00000251849
 ENST00000442415  EntrezGene:5894  HGNC:9829  HPA002640  ILMN_1813489
 L7RRS6  LRG_413  LRG_413t1  MIM:164760  NM_002880
 NP_002871  PF00130  PF02196  PF07714  PH_hs_0039978
 PR00008  RAF1  RAF1-001  RAF1-007  SM00109
 SM00220  SM00455  uc003bxf.5  uc062gvt.1  UPI0000049CFC
 UPI000178DE79  X03484_at  XM_005265355  XM_005265357  XM_005265358
 XM_011533974  XM_011533975  XP_005265412  XP_005265414  XP_005265415
 XP_011532276  XP_011532277
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name Coordinate Modification PsiMod
O-phospho-L-serine at 259 259
O-phospho-L-serine at 621 621
Cross References
RefSeq
UCSC human
ZINC_target
GeneCards
DOCK Blaster
PRO
HMDB_protein
Protein Data Bank
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.957 P01112 RASH_HUMAN 17
0.954 P63104 1433Z_HUMAN 16
0.928 P31946 1433B_HUMAN 18
0.88 Q02750 MP2K1_HUMAN 31
0.878 P15056 BRAF_HUMAN 46
0.773 Q04917 1433F_HUMAN 6
0.744 P27348 1433T_HUMAN 4
0.708 Q16543 CDC37_HUMAN 4
0.688 P08238 HS90B_HUMAN 3
0.688 P04049 RAF1_HUMAN 4
0.669 P31947 1433S_HUMAN 3
0.669 P61981 1433G_HUMAN 3
0.667 P36507 MP2K2_HUMAN 3
0.664 P30086 PEBP1_HUMAN 7
0.659 P62258 1433E_HUMAN 3
0.643 Q13418 ILK_HUMAN 3
0.623 P62834 RAP1A_HUMAN 2
0.597 Q96S96 PEBP4_HUMAN 4
0.589 P31749 AKT1_HUMAN 2
0.589 Q92934 BAD_HUMAN 2
0.576 P11021 GRP78_HUMAN 4
0.558 Q13177 PAK2_HUMAN 2
0.556 O39474 O39474_9HEPC 4
0.547 Q3ZCQ8 TIM50_HUMAN 4
0.544 P01116-2 KRAS 2
0.527 O43852 CALU_HUMAN 2
0.508 Q99933 BAG1_HUMAN 2
0.508 P03495 NS1_I72A2 2
0.499 Q9ESN9-2 MAPK8IP3 2
0.499 P01120 RAS2_YEAST 2
0.499 P28301 LYOX_MOUSE 2
0.488 P05783 K1C18_HUMAN 5
0.456 P67775 PP2AA_HUMAN 2
0.456 Q13362 2A5G_HUMAN 2