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MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1

Stable Identifier
R-HSA-109822
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

At the beginning of this reaction, 1 molecule of 'ATP', and 1 molecule of 'GRB2:SOS:SHC-P' are present. At the end of this reaction, 1 molecule of 'GRB2:SHC-P', 1 molecule of 'phospho-SOS', and 1 molecule of 'ADP' are present.

Literature References
PubMed ID Title Journal Year
7739560 Insulin-stimulated disassociation of the SOS-Grb2 complex. Mol Cell Biol 1995
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
kinase activity of MAPK3,(MAPK1) [cytosol]
Physical Entity
Activity
Orthologous Events