Reactome: A Curated Pathway Database

Binding of ERCC1:ERCC4 (ERCC1:XPF) to preincision complex (R-HSA-109953)

Species Homo sapiens

Summation

ERCC1-XPF complex with 5' endonuclease activity binds to the pre-incision complex around the bubble structure to form an active incision complex.

Locations in the PathwayBrowser
Additional Information
Compartment nucleoplasm
GO Biological Process nucleotide-excision repair, preincision complex stabilization (0006293)
Literature References
pubMedId Title Journal Year
10214908 DNA damage recognition during nucleotide excision repair in mammalian cells. Biochimie 1999