Reactome: A Curated Pathway Database

Displacement of stalled Pol II from the lesion site (R-HSA-109974)

Species Homo sapiens

Summation

At the beginning of this reaction, 1 molecule of 'Transcription-coupled (TC) repair complex', and 1 molecule of 'Stalled Pol II complex with damaged DNA hybrid' are present. At the end of this reaction, 1 molecule of 'Transcription-coupled (TC) repair complex', 1 molecule of 'Stalled Pol II in TC-NER', and 1 molecule of 'damaged DNA substrate:nascent mRNA hybrid' are present.

This reaction takes place in the 'nucleus'.

Locations in the PathwayBrowser
Additional Information
Compartment nucleoplasm