Reactome will be unavailable due to host maintenance from Friday, April 27 at 6pm to Sunday, April 29 at 11:55pm.

During the outage, you may wish to use our mirror site at reactome.ncpsb.org.

Activation and oligomerization of BAK protein

Stable Identifier
R-HSA-111452
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

tBID binds to its mitochondrial partner BAK to release cytochrome c. Activated tBID results in an allosteric activation of BAK. This may induce its intramembranous oligomerization into a pore for cytochrome c efflux.

Participants
Participant Of
Event Information