There will be a maintenance on OICR IT systems starting Friday Dec 15 at 6PM EST until midnight Sunday Dec 17; Reactome will be affected by this downtime

Service under maintenance from Friday Dec 15 at 6PM EST until midnight Sunday Dec 17

Activation and oligomerization of BAK protein

Stable Identifier
R-HSA-111452
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

tBID binds to its mitochondrial partner BAK to release cytochrome c. Activated tBID results in an allosteric activation of BAK. This may induce its intramembranous oligomerization into a pore for cytochrome c efflux.

Participants
Participant Of
Event Information
Orthologous Events
Cross References
BioModels Database