PKA-mediated phosphorylation of CREB

Stable Identifier
R-HSA-111931
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Cyclic adenosine 3',5'-monophosphate (cAMP) induces gene transcription through activation of cAMP-dependent protein kinase (PKA), and subsequent phosphorylation of the transcription factor cAMP response element-binding protein, CREB, at serine-133.

Literature References
PubMed ID Title Journal Year
15337521 What turns CREB on? Cell Signal 2004
16125054 The cAMP signalling pathway activates CREB through PKA, p38 and MSK1 in NIH 3T3 cells Cell Signal 2005
Participants
Participant Of
Orthologous Events