Reactome: A Curated Pathway Database
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Ca-dependent events

Stable Identifier
R-HSA-111996
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Calcium, as the ion Ca2+, is essential in many biological processes. The majority of Ca2+ in many organisms is bound to phosphates which form skeletal structures and also buffer Ca2+ levels in extracellular fluids (typically 1 millimolar). Intracellular free Ca2+, by contrast, is 10,000 times lower than the outside of the cell (typically 10 micromolar). This concentration gradient is used to import Ca2+ into cells where it acts as a second messenger.

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
Orthologous Events