Reactome: A Curated Pathway Database
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Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels

Stable Identifier
R-HSA-112308
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

The action potential travels down the axon and reaches the pre-synaptic terminal depolarizing the membrane in the pre-synaptic terminal. The depolarization causes the voltage-gated Ca2+ channels to open allowing the influx of Ca2+ that signals the release of neurotransmitter into the synaptic cleft.

Participants
Participant Of
Orthologous Events