Reactome: A Curated Pathway Database

Neurotransmitter Clearance In The Synaptic Cleft (R-HSA-112311) [Homo sapiens]


Neurotransmitter released in the synaptic cleft binds to specific receptors on the post-synaptic cell and the excess of the neurotransmitter is cleared to prevent over activation of the post-synaptic cell. The neurotransmitter is cleared by either re-uptake by the pre-synaptic neuron, diffusion in the perisynaptic area, uptake by astrocytes surrounding the synaptic cleft or enzymatic degradation of the neurotransmitter.
This topic will be annotated in a future release.

Additional Information
GO Biological Process neurotransmitter biosynthetic process (0042136)