Reactome: A Curated Pathway Database

Neurotransmitter Clearance In The Synaptic Cleft

Stable Identifier
R-HSA-112311
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Neurotransmitter released in the synaptic cleft binds to specific receptors on the post-synaptic cell and the excess of the neurotransmitter is cleared to prevent over activation of the post-synaptic cell. The neurotransmitter is cleared by either re-uptake by the pre-synaptic neuron, diffusion in the perisynaptic area, uptake by astrocytes surrounding the synaptic cleft or enzymatic degradation of the neurotransmitter.
This topic will be annotated in a future release.

Participants
Participant Of
Orthologous Events
Cross References
BioModels Database