Reactome: A Curated Pathway Database
Attention
The EBI data centre will be shutting down from the afternoon (BST) of Friday 26th August until the afternoon of Tuesday 30th August 2016 for essential maintenance. This might have an impact on some Reactome services and we apologize for any inconvenience.

IRS-mediated signalling

Stable Identifier
R-HSA-112399
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Release of phospho-IRS from the insulin receptor triggers a cascade of signalling events via PI3K, SOS, RAF and the MAP kinases.

Participants
Participant Of
Orthologous Events