Reactome: A Curated Pathway Database

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites (R-HSA-113442)

Species Homo sapiens


Productive transcription is accompanied by retractive RNase activity at U-tract pause sites and at the terminator. The principal cleavage products are dinucleotides, and they are produced in large stoichiometric excess over complete transcripts, despite the rapid overall rate of productive RNA chain elongation. This event is inferred from an event in Saccharomyces cerevisiae.

Locations in the PathwayBrowser
Additional Information
Compartment nucleoplasm
GO Biological Process transcription from RNA polymerase III promoter (0006383)