Reactome: A Curated Pathway Database

RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites

Stable Identifier
R-HSA-113442
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Productive transcription is accompanied by retractive RNase activity at U-tract pause sites and at the terminator. The principal cleavage products are dinucleotides, and they are produced in large stoichiometric excess over complete transcripts, despite the rapid overall rate of productive RNA chain elongation. This event is inferred from an event in Saccharomyces cerevisiae.

Participants
Participant Of
Inferred From