Reactome: A Curated Pathway Database
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Downstream signaling events of B Cell Receptor (BCR)

Stable Identifier
R-HSA-1168372
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Second messengers (calcium, diacylglycerol, inositol 1,4,5-trisphosphate, and phosphatidyinositol 3,4,5-trisphosphate) trigger signaling pathways: NF-kappaB is activated via protein kinase C beta, RAS via RasGRP proteins, NF-AT via calcineurin, and AKT via PDK1 (reviewed in Shinohara and Kurosaki 2009, Stone 2006).

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
Orthologous Events