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Downstream signaling events of B Cell Receptor (BCR)

Stable Identifier
R-HSA-1168372
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Second messengers (calcium, diacylglycerol, inositol 1,4,5-trisphosphate, and phosphatidyinositol 3,4,5-trisphosphate) trigger signaling pathways: NF-kappaB is activated via protein kinase C beta, RAS via RasGRP proteins, NF-AT via calcineurin, and AKT via PDK1 (reviewed in Shinohara and Kurosaki 2009, Stone 2006).

Literature References
PubMed ID Title Journal Year
19909372 Comprehending the complex connection between PKCbeta, TAK1, and IKK in BCR signaling Immunol Rev 2009
17052215 Regulation of Ras in lymphocytes: get a GRP Biochem Soc Trans 2006
Participants
Participant Of