Reactome: A Curated Pathway Database
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ROS, RNS production in response to bacteria

Stable Identifier
R-HSA-1222556
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

When engulfed by macrophages, microorganisms are exposed to a number of host defense mechanisms within the resulting phagosome and through its subsequent fusion with lysosomes. These include the production of reactive oxygen and nitrogen species (ROS and RNS) (Fang FC et al. 2004; Kohchi C et al. 2009; Gostner JM et al. 2013; Vatansever F et al. 2013)

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
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Orthologous Events