Reactome: A Curated Pathway Database

Negative Regulation of MDA5 signaling (R-GGA-1227888) [Gallus gallus]

Pathway
Summation

Antiviral responses must be tightly regulated in order to prevent uncontrolled production of type I IFN that may lead to damage of host's cells and tissues.

Additional Information
GO Biological Process negative regulation of innate immune response (0045824)
Literature References
pubMedId Title Journal Year
18703349 Negative regulation of cytoplasmic RNA-mediated antiviral signaling Cytokine 2008