Reactome: A Curated Pathway Database

CO-H+-HBA1 (R-HSA-1237026)

Species Homo sapiens

Additional Information
External reference name HBA1
External reference id P69905
Synonyms Protonated Carbamino Hemoglobin subunit alpha, HBA1
Compartment cytosol
Other Identifiers 0003520368, 0004200088, 11754267_x_at, 1A00, 1A01, 1A0U, 1A0Z, 1A3N, 1A3O, 1A9W, 1ABW, 1ABY, 1AJ9, 1B86, 1BAB, 1BBB, 1BIJ, 1BUW, 1BZ0, 1BZ1, 1BZZ, 1C7B, 1C7C, 1C7D, 1CLS, 1CMY, 1COH, 1DKE, 1DXT, 1DXU, 1DXV, 1FDH, 1FN3, 1G9V, 1GBU, 1GBV, 1GLI, 1GZX, 1HAB, 1HAC, 1HBA, 1HBB, 1HBS, 1HCO, 1HDB, 1HGA, 1HGB, 1HGC, 1HHO, 1IRD, 1J3Y, 1J3Z, 1J40, 1J41, 1J7S, 1J7W, 1J7Y, 1JY7, 1K0Y, 1K1K, 1KD2, 1LFL, 1LFQ, 1LFT, 1LFV, 1LFY, 1LFZ, 1LJW, 1M9P, 1MKO, 1NEJ, 1NIH, 1NQP, 1O1I, 1O1J, 1O1K, 1O1L, 1O1M, 1O1N, 1O1O, 1O1P, 1QI8, 1QSH, 1QSI, 1QXD, 1QXE, 1R1X, 1R1Y, 1RPS, 1RQ3, 1RQ4, 1RQA, 1RVW, 1SDK, 1SDL, 1SHR, 1SI4, 1THB, 1UIW, 1VWT, 1XXT, 1XY0, 1XYE, 1XZ2, 1XZ4, 1XZ5, 1XZ7, 1XZU, 1XZV, 1Y01, 1Y09, 1Y0A, 1Y0C, 1Y0D, 1Y0T, 1Y0W, 1Y22, 1Y2Z, 1Y31, 1Y35, 1Y45, 1Y46, 1Y4B, 1Y4F, 1Y4G, 1Y4P, 1Y4Q, 1Y4R, 1Y4V, 1Y5F, 1Y5J, 1Y5K, 1Y7C, 1Y7D, 1Y7G, 1Y7Z, 1Y83, 1Y85, 1Y8W, 1YDZ, 1YE0, 1YE1, 1YE2, 1YEN, 1YEO, 1YEQ, 1YEU, 1YEV, 1YFF, 1YG5, 1YGD, 1YGF, 1YH9, 1YHE, 1YHR, 1YIE, 1YIH, 1YVQ, 1YVT, 1YZI, 1Z8U, 204018_3p_x_at, 204018_x_at, 209458_3p_x_at, 209458_x_at, 211699_3p_x_at, 211699_x_at, 211745_3p_x_at, 211745_x_at, 214414_3p_x_at, 214414_x_at, 217414_3p_x_at, 217414_x_at, 2D5Z, 2D60, 2DN1, 2DN2, 2DN3, 2DXM, 2H35, 2HBC, 2HBD, 2HBE, 2HBF, 2HBS, 2HCO, 2HHB, 2HHD, 2HHE, 2M6Z, 2W6V, 2W72, 2YRS, 3039, 3040, 31525_s_at, 3B75, 3D17, 3D7O, 3DUT, 3HHB, 3HXN, 3IA3, 3IC0, 3IC2, 3KMF, 3NL7, 3NMM, 3ODQ, 3ONZ, 3OO4, 3OO5, 3OVU, 3P5Q, 3QJB, 3QJC, 3QJD, 3QJE, 3R5I, 3S48, 3S65, 3S66, 3SZK, 3WCP, 3WHM, 4FC3, 4HHB, 4IJ2, 4L7Y, 4M4A, 4M4B, 4MQC, 4MQG, 4MQH, 4MQI, 4MQJ, 4MQK, 4N7N, 4N7O, 4N7P, 4N8T, 4NI0, 4NI1, 4WJG, 4X0I, 4X0L, 6HBW, A_23_P26457, A_23_P37856, A_24_P142305, A_33_P3258362, AAB59407, AAB59408, AAC72839, AAC97373, AAF72612, AAH05931, AAH08572, AAH32122, AAH50661, AAI01847, AAI01849, AAK37554, AAK61215, AAK61216, AAM83102, AAN04486, ABD95910, ABD95911, ABF56144, ABF56145, ACZ54507, ADV78002, AE006462, AF097635, AF105974, AF230076, AF349571, AF525460, AF536204, AK223392, BAD97112, BC005931, BC008572, BC032122, BC050661, BC101846, BC101848, CAA23748, CAA23750, CAA23752, CAA23774, CAB032534, CAB038417, CAB06554, CAB06555, CCDS10398, CCDS10399, CH471112, D1MGQ2, DQ431198, DQ499017, DQ499018, EAW85863, ENSG00000188536, ENSG00000206172, ENSP00000251595, ENSP00000322421, ENST00000251595, ENST00000320868, EntrezGene:3039, EntrezGene:3040, g13543547_3p_x_at, g13650073_3p_s_at, g4038449_3p_s_at, g6715603_3p_s_at, GE79916, GU145033, HBA1, HBA1-001, HBA2, HBA2-001, HGNC:4823, HGNC:4824, HPA043780, HQ156224, Hs.272572.2.S1_3p_s_at, ILMN_1667796, ILMN_3240144, IPR000971, IPR002338, IPR002339, IPR009050, J00153, MIM:140700, MIM:141800, MIM:141850, MIM:604131, MIM:613978, NM_000517, NM_000558, NP_000508, NP_000549, OTTHUMP00000066291, OTTHUMP00000066501, PF00042, PH_hs_0030402, PH_hs_0033731, PR00612, PR00815, REACT_111217, REACT_120969, REACT_121329, REACT_121380, REACT_160163, REACT_160300, uc002cfv.4, uc002cfx.1, UPI0000000239, V00488, V00491, V00493, V00516, Z84721, Z84721_cds2_at
Secondary Identifiers HBA_HUMAN, P01922, Q1HDT5, Q3MIF5, Q53F97, Q96KF1, Q9NYR7, Q9UCM0
Gene Names HBA1, , , HBA2
Chain initiator methionine:1, chain:2-142
This entry is a component of:
hasComponent
Reference Genes
Database Identifier
dbSNP Gene 3039, 3040
CTD Gene 3039, 3040
BioGPS Gene 3039, 3040
NCBI Gene 3039, 3040
ENSEMBL ENSG00000188536
KEGG Gene 3039, 3040
Orphanet 16185, 16819
OMIM 141800
Reference Transcripts
Database Identifier
RefSeq NM_000517
Cross References
Database Identifier
RefSeq NP_000508, NP_000549
DOCK Blaster 1Y01, 1Z8U, 1A00, 1A01, 1A0U, 1A0Z, 1A3N, 1A3O, 1A9W, 1ABW, 1ABY, 1AJ9, 1B86, 1BAB, 1BBB, 1BIJ, 1BUW, 1BZ0, 1BZ1, 1BZZ, 1C7B, 1C7C, 1C7D, 1CLS, 1CMY, 1COH, 1DKE, 1DXT, 1DXU, 1DXV, 1FDH, 1FN3, 1G9V, 1GBU, 1GBV, 1GLI, 1GZX, 1HAB, 1HAC, 1HBA, 1HBB, 1HBS, 1HCO, 1HDB, 1HGA, 1HGB, 1HGC, 1HHO, 1IRD, 1J3Y, 1J3Z, 1J40, 1J41, 1J7S, 1J7W, 1J7Y, 1JY7, 1K0Y, 1K1K, 1KD2, 1LFL, 1LFQ, 1LFT, 1LFV, 1LFY, 1LFZ, 1LJW, 1M9P, 1MKO, 1NEJ, 1NIH, 1NQP, 1O1I, 1O1J, 1O1K, 1O1L, 1O1M, 1O1N, 1O1O, 1O1P, 1QI8, 1QSH, 1QSI, 1QXD, 1QXE, 1R1X, 1R1Y, 1RPS, 1RQ3, 1RQ4, 1RQA, 1RVW, 1SDK, 1SDL, 1SHR, 1SI4, 1THB, 1UIW, 1VWT, 1XXT, 1XY0, 1XYE, 1XZ2, 1XZ4, 1XZ5, 1XZ7, 1XZU, 1XZV, 1Y09, 1Y0A, 1Y0C, 1Y0D, 1Y0T, 1Y0W, 1Y22, 1Y2Z, 1Y31, 1Y35, 1Y45, 1Y46, 1Y4B, 1Y4F, 1Y4G, 1Y4P, 1Y4Q, 1Y4R, 1Y4V, 1Y5F, 1Y5J, 1Y5K, 1Y7C, 1Y7D, 1Y7G, 1Y7Z, 1Y83, 1Y85, 1Y8W, 1YDZ, 1YE0, 1YE1, 1YE2, 1YEN, 1YEO, 1YEQ, 1YEU, 1YEV, 1YFF, 1YG5, 1YGD, 1YGF, 1YH9, 1YHE, 1YHR, 1YIE, 1YIH, 1YVQ, 1YVT, 1YZI, 2D5Z, 2D60, 2DN1, 2DN2, 2DN3, 2H35, 2HBC, 2HBD, 2HBE, 2HBF, 2HBS, 2HCO, 2HHD, 2HHE, 4HHB, 6HBW
HMDB_protein HMDBP01626
PRO P69905
GeneCards P69905
UCSC human P69905
Protein Data Bank 1Y01, 1Z8U, 1A00, 1A01, 1A0U, 1A0Z, 1A3N, 1A3O, 1A9W, 1ABW, 1ABY, 1AJ9, 1B86, 1BAB, 1BBB, 1BIJ, 1BUW, 1BZ0, 1BZ1, 1BZZ, 1C7B, 1C7C, 1C7D, 1CLS, 1CMY, 1COH, 1DKE, 1DXT, 1DXU, 1DXV, 1FDH, 1FN3, 1G9V, 1GBU, 1GBV, 1GLI, 1GZX, 1HAB, 1HAC, 1HBA, 1HBB, 1HBS, 1HCO, 1HDB, 1HGA, 1HGB, 1HGC, 1HHO, 1IRD, 1J3Y, 1J3Z, 1J40, 1J41, 1J7S, 1J7W, 1J7Y, 1JY7, 1K0Y, 1K1K, 1KD2, 1LFL, 1LFQ, 1LFT, 1LFV, 1LFY, 1LFZ, 1LJW, 1M9P, 1MKO, 1NEJ, 1NIH, 1NQP, 1O1I, 1O1J, 1O1K, 1O1L, 1O1M, 1O1N, 1O1O, 1O1P, 1QI8, 1QSH, 1QSI, 1QXD, 1QXE, 1R1X, 1R1Y, 1RPS, 1RQ3, 1RQ4, 1RQA, 1RVW, 1SDK, 1SDL, 1SHR, 1SI4, 1THB, 1UIW, 1VWT, 1XXT, 1XY0, 1XYE, 1XZ2, 1XZ4, 1XZ5, 1XZ7, 1XZU, 1XZV, 1Y09, 1Y0A, 1Y0C, 1Y0D, 1Y0T, 1Y0W, 1Y22, 1Y2Z, 1Y31, 1Y35, 1Y45, 1Y46, 1Y4B, 1Y4F, 1Y4G, 1Y4P, 1Y4Q, 1Y4R, 1Y4V, 1Y5F, 1Y5J, 1Y5K, 1Y7C, 1Y7D, 1Y7G, 1Y7Z, 1Y83, 1Y85, 1Y8W, 1YDZ, 1YE0, 1YE1, 1YE2, 1YEN, 1YEO, 1YEQ, 1YEU, 1YEV, 1YFF, 1YG5, 1YGD, 1YGF, 1YH9, 1YHE, 1YHR, 1YIE, 1YIH, 1YVQ, 1YVT, 1YZI, 2D5Z, 2D60, 2DN1, 2DN2, 2DN3, 2H35, 2HBC, 2HBD, 2HBE, 2HBF, 2HBS, 2HCO, 2HHD, 2HHE, 4HHB, 6HBW
ModifiedResidues
Name Coordinate Modification PsiMod Name PsiMod Identifier PsiMod Definition
carboxylated residue at 2 2 carboxylated residue 01152 A protein modification that effectively replaces a hydrogen atom with a carboxylic acid group.
protonated residue at unknown position protonated residue 01699 A protein modification that effectively adds a hydrogen cation, a proton, forming a cationic residue.
Inferred Entries
Inferred to