Reactome: A Curated Pathway Database

CO-H+-HBA1 (R-HSA-1237026) [Homo sapiens]

Reference Gene Product
Additional Information
External reference name HBA1
External reference id P69905
Synonyms Protonated Carbamino Hemoglobin subunit alpha, HBA1
Compartment cytosol
Other Identifiers
 0003520368  0004200088  11754267_x_at  1A00  1A01
 1A0U  1A0Z  1A3N  1A3O  1A9W
 1ABW  1ABY  1AJ9  1B86  1BAB
 1BBB  1BIJ  1BUW  1BZ0  1BZ1
 1BZZ  1C7B  1C7C  1C7D  1CLS
 1CMY  1COH  1DKE  1DXT  1DXU
 1DXV  1FDH  1FN3  1G9V  1GBU
 1GBV  1GLI  1GZX  1HAB  1HAC
 1HBA  1HBB  1HBS  1HCO  1HDB
 1HGA  1HGB  1HGC  1HHO  1IRD
 1J3Y  1J3Z  1J40  1J41  1J7S
 1J7W  1J7Y  1JY7  1K0Y  1K1K
 1KD2  1LFL  1LFQ  1LFT  1LFV
 1LFY  1LFZ  1LJW  1M9P  1MKO
 1NEJ  1NIH  1NQP  1O1I  1O1J
 1O1K  1O1L  1O1M  1O1N  1O1O
 1O1P  1QI8  1QSH  1QSI  1QXD
 1QXE  1R1X  1R1Y  1RPS  1RQ3
 1RQ4  1RQA  1RVW  1SDK  1SDL
 1SHR  1SI4  1THB  1UIW  1VWT
 1XXT  1XY0  1XYE  1XZ2  1XZ4
 1XZ5  1XZ7  1XZU  1XZV  1Y01
 1Y09  1Y0A  1Y0C  1Y0D  1Y0T
 1Y0W  1Y22  1Y2Z  1Y31  1Y35
 1Y45  1Y46  1Y4B  1Y4F  1Y4G
 1Y4P  1Y4Q  1Y4R  1Y4V  1Y5F
 1Y5J  1Y5K  1Y7C  1Y7D  1Y7G
 1Y7Z  1Y83  1Y85  1Y8W  1YDZ
 1YE0  1YE1  1YE2  1YEN  1YEO
 1YEQ  1YEU  1YEV  1YFF  1YG5
 1YGD  1YGF  1YH9  1YHE  1YHR
 1YIE  1YIH  1YVQ  1YVT  1YZI
 1Z8U  204018_3p_x_at  204018_x_at  209458_3p_x_at  209458_x_at
 211699_3p_x_at  211699_x_at  211745_3p_x_at  211745_x_at  214414_3p_x_at
 214414_x_at  217414_3p_x_at  217414_x_at  2D5Z  2D60
 2DN1  2DN2  2DN3  2DXM  2H35
 2HBC  2HBD  2HBE  2HBF  2HBS
 2HCO  2HHB  2HHD  2HHE  2M6Z
 2W6V  2W72  2YRS  3039  3040
 31525_s_at  3B75  3D17  3D7O  3DUT
 3HHB  3HXN  3IA3  3IC0  3IC2
 3KMF  3NL7  3NMM  3ODQ  3ONZ
 3OO4  3OO5  3OVU  3P5Q  3QJB
 3QJC  3QJD  3QJE  3R5I  3S48
 3S65  3S66  3SZK  3WCP  3WHM
 4FC3  4HHB  4IJ2  4L7Y  4M4A
 4M4B  4MQC  4MQG  4MQH  4MQI
 4MQJ  4MQK  4N7N  4N7O  4N7P
 4N8T  4NI0  4NI1  4ROL  4ROM
 4WJG  4X0I  4X0L  4XS0  5E29
 6HBW  A_23_P26457  A_23_P37856  A_24_P142305  A_33_P3258362
 AAB59407  AAB59408  AAC72839  AAC97373  AAF72612
 AAH05931  AAH08572  AAH32122  AAH50661  AAI01847
 AAI01849  AAK37554  AAK61215  AAK61216  AAM83102
 AAN04486  ABD95910  ABD95911  ABF56144  ABF56145
 ACZ54507  ADV78002  AE006462  AF097635  AF105974
 AF230076  AF349571  AF525460  AF536204  AK223392
 BAD97112  BC005931  BC008572  BC032122  BC050661
 BC101846  BC101848  CAA23748  CAA23750  CAA23752
 CAA23774  CAB032534  CAB038417  CAB06554  CAB06555
 CCDS10398  CCDS10399  CH471112  D1MGQ2  DQ431198
 DQ499017  DQ499018  EAW85863  ENSG00000188536  ENSG00000206172
 ENSP00000251595  ENSP00000322421  ENST00000251595  ENST00000320868  EntrezGene:3039
 EntrezGene:3040  g13543547_3p_x_at  g13650073_3p_s_at  G3V1N2  g4038449_3p_s_at
 g6715603_3p_s_at  GE79916  GU145033  HBA1  HBA1-001
 HBA2  HBA2-001  HGNC:4823  HGNC:4824  HPA043780
 HQ156224  Hs.272572.2.S1_3p_s_at  ILMN_1667796  IPR000971  IPR002338
 IPR002339  IPR009050  J00153  MIM:141800  MIM:141850
 NM_000517  NM_000558  NP_000508  NP_000549  OTTHUMP00000066291
 OTTHUMP00000066501  PF00042  PH_hs_0030402  PH_hs_0033731  PR00612
 PR00815  R-HSA-1237044  R-HSA-1247673  R-HSA-1430728  R-HSA-1480926
 R-HSA-2168880  R-HSA-2173782  R-HSA-5653656  uc002cfv.4  uc002cfx.2
 UPI0000000239  V00488  V00491  V00493  V00516
 Z84721  Z84721_cds2_at
Secondary Identifiers HBA_HUMAN, P01922, Q1HDT5, Q3MIF5, Q53F97, Q96KF1, Q9NYR7, Q9UCM0
Gene Names HBA1, HBA2
Chain initiator methionine:1, chain:2-142
This entry is a component of:
hasComponent
Reference Genes
Database Identifier
dbSNP Gene 3039
CTD Gene 3039
BioGPS Gene 3039
NCBI Gene 3039
ENSEMBL ENSG00000206172
KEGG Gene HBA1, HBA2
Orphanet 16819, 16185
Reference Transcripts
Database Identifier
RefSeq NM_000558
Cross References
Database Identifier
RefSeq NP_000549, NP_000508
DOCK Blaster 5E29, 6HBW, 4X0L, 4XS0, 4WJG, 4X0I, 4ROL, 4ROM, 4NI0, 4NI1, 4N7P, 4N8T, 4N7N, 4N7O, 4MQJ, 4MQK, 4MQH, 4MQI, 4MQC, 4MQG, 4M4A, 4M4B, 4IJ2, 4L7Y, 4FC3, 4HHB, 3WCP, 3WHM, 3S66, 3SZK, 3S48, 3S65, 3QJE, 3R5I, 3QJC, 3QJD, 3P5Q, 3QJB, 3OO4, 3OO5, 3ODQ, 3ONZ, 3NL7, 3NMM, 3IC2, 3KMF, 3HXN, 3IC0, 3DUT, 3HHB, 3D17, 3D7O, 2YRS, 3B75, 2W6V, 2W72, 2HHE, 2M6Z, 2HHB, 2HHD, 2HBS, 2HCO, 2HBE, 2HBF, 2HBC, 2HBD, 2DXM, 2H35, 2DN2, 2DN3, 2D60, 2DN1, 1YZI, 2D5Z, 1YVQ, 1YVT, 1YIE, 1YIH, 1YHE, 1YHR, 1YGF, 1YH9, 1YG5, 1YGD, 1YEV, 1YFF, 1YEQ, 1YEU, 1YEN, 1YEO, 1YE1, 1YE2, 1YDZ, 1YE0, 1Y85, 1Y8W, 1Y7Z, 1Y83, 1Y7D, 1Y7G, 1Y5K, 1Y7C, 1Y5F, 1Y5J, 1Y4V, 1Y4Q, 1Y4R, 1Y4G, 1Y4P, 1Y4B, 1Y4F, 1Y45, 1Y46, 1Y31, 1Y35, 1Y22, 1Y2Z, 1Y0T, 1Y0W, 1Y0C, 1Y0D, 1Y09, 1Y0A, 1XZU, 1XZV, 1XZ5, 1XZ7, 1XZ2, 1XZ4, 1XY0, 1XYE, 1VWT, 1XXT, 1THB, 1UIW, 1SHR, 1SI4, 1SDK, 1SDL, 1RQA, 1RVW, 1RQ3, 1RQ4, 1R1Y, 1RPS, 1QXE, 1R1X, 1QSI, 1QXD, 1QI8, 1QSH, 1O1O, 1O1P, 1O1M, 1O1N, 1O1K, 1O1L, 1O1I, 1O1J, 1NIH, 1NQP, 1MKO, 1NEJ, 1LJW, 1M9P, 1LFY, 1LFZ, 1LFT, 1LFV, 1LFL, 1LFQ, 1K1K, 1KD2, 1JY7, 1K0Y, 1J7W, 1J7Y, 1J41, 1J7S, 1J3Z, 1J40, 1IRD, 1J3Y, 1HGC, 1HHO, 1HGA, 1HGB, 1HCO, 1HDB, 1HBB, 1HBS, 1HAC, 1HBA, 1GZX, 1HAB, 1GBV, 1GLI, 1G9V, 1GBU, 1FDH, 1FN3, 1DXU, 1DXV, 1DXT, 1COH, 1DKE, 1CLS, 1CMY, 1C7C, 1C7D, 1BZZ, 1C7B, 1BZ0, 1BZ1, 1BIJ, 1BUW, 1BAB, 1BBB, 1AJ9, 1B86, 1ABW, 1ABY, 1A3O, 1A9W, 1A0Z, 1A3N, 1A0U, 1A00, 1A01, 3OVU, 3IA3, 1Y01, 1Z8U
HMDB_protein HMDBP01626
PRO P69905
GeneCards P69905
UCSC human P69905
Protein Data Bank 5E29, 6HBW, 4X0L, 4XS0, 4WJG, 4X0I, 4ROL, 4ROM, 4NI0, 4NI1, 4N7P, 4N8T, 4N7N, 4N7O, 4MQJ, 4MQK, 4MQH, 4MQI, 4MQC, 4MQG, 4M4A, 4M4B, 4IJ2, 4L7Y, 4FC3, 4HHB, 3WCP, 3WHM, 3S66, 3SZK, 3S48, 3S65, 3QJE, 3R5I, 3QJC, 3QJD, 3P5Q, 3QJB, 3OO4, 3OO5, 3ODQ, 3ONZ, 3NL7, 3NMM, 3IC2, 3KMF, 3HXN, 3IC0, 3DUT, 3HHB, 3D17, 3D7O, 2YRS, 3B75, 2W6V, 2W72, 2HHE, 2M6Z, 2HHB, 2HHD, 2HBS, 2HCO, 2HBE, 2HBF, 2HBC, 2HBD, 2DXM, 2H35, 2DN2, 2DN3, 2D60, 2DN1, 1YZI, 2D5Z, 1YVQ, 1YVT, 1YIE, 1YIH, 1YHE, 1YHR, 1YGF, 1YH9, 1YG5, 1YGD, 1YEV, 1YFF, 1YEQ, 1YEU, 1YEN, 1YEO, 1YE1, 1YE2, 1YDZ, 1YE0, 1Y85, 1Y8W, 1Y7Z, 1Y83, 1Y7D, 1Y7G, 1Y5K, 1Y7C, 1Y5F, 1Y5J, 1Y4V, 1Y4Q, 1Y4R, 1Y4G, 1Y4P, 1Y4B, 1Y4F, 1Y45, 1Y46, 1Y31, 1Y35, 1Y22, 1Y2Z, 1Y0T, 1Y0W, 1Y0C, 1Y0D, 1Y09, 1Y0A, 1XZU, 1XZV, 1XZ5, 1XZ7, 1XZ2, 1XZ4, 1XY0, 1XYE, 1VWT, 1XXT, 1THB, 1UIW, 1SHR, 1SI4, 1SDK, 1SDL, 1RQA, 1RVW, 1RQ3, 1RQ4, 1R1Y, 1RPS, 1QXE, 1R1X, 1QSI, 1QXD, 1QI8, 1QSH, 1O1O, 1O1P, 1O1M, 1O1N, 1O1K, 1O1L, 1O1I, 1O1J, 1NIH, 1NQP, 1MKO, 1NEJ, 1LJW, 1M9P, 1LFY, 1LFZ, 1LFT, 1LFV, 1LFL, 1LFQ, 1K1K, 1KD2, 1JY7, 1K0Y, 1J7W, 1J7Y, 1J41, 1J7S, 1J3Z, 1J40, 1IRD, 1J3Y, 1HGC, 1HHO, 1HGA, 1HGB, 1HCO, 1HDB, 1HBB, 1HBS, 1HAC, 1HBA, 1GZX, 1HAB, 1GBV, 1GLI, 1G9V, 1GBU, 1FDH, 1FN3, 1DXU, 1DXV, 1DXT, 1COH, 1DKE, 1CLS, 1CMY, 1C7C, 1C7D, 1BZZ, 1C7B, 1BZ0, 1BZ1, 1BIJ, 1BUW, 1BAB, 1BBB, 1AJ9, 1B86, 1ABW, 1ABY, 1A3O, 1A9W, 1A0Z, 1A3N, 1A0U, 1A00, 1A01, 3OVU, 3IA3, 1Y01, 1Z8U
ModifiedResidues
Name Coordinate Modification PsiMod Name PsiMod Identifier PsiMod Definition
carboxylated residue at 2 2 carboxylated residue 01152 A protein modification that effectively replaces a hydrogen atom with a carboxylic acid group.
protonated residue at unknown position protonated residue 01699 A protein modification that effectively adds a hydrogen cation, a proton, forming a cationic residue.
Interactions
Confidence Score Interactor Accession Interactor Name Evidences
0.949 P68871 HBB 20
0.556 Q2TAC2 CCD57 3
0.556 Q6A162 K1C40 3