Reactome: A Curated Pathway Database

Cytokine Signaling in Immune system

Stable Identifier
R-HSA-1280215
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Cytokines are small proteins that regulate and mediate immunity, inflammation, and hematopoiesis. They are secreted in response to immune stimuli, and usually act briefly, locally, at very low concentrations. Cytokines bind to specific membrane receptors, which then signal the cell via second messengers, to regulate cellular activity.

Literature References
PubMed ID Title Journal Year
  Cytokine Reference   2002
12613569 Cytokines and chemokines in autoimmune disease: an overview Adv Exp Med Biol 2003
  COPE    
  IMMPORT:Bioinformatics for the future of immunology    
Participants
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Orthologous Events