Reactome: A Curated Pathway Database

G protein gated Potassium channels (R-HSA-1296059) [Homo sapiens]


Inwardly rectifying G protein activated K+ channels (GIRK) are tetrameric assemblies of Ki3 3 family subunits (Kir 3.1, 3.2 3.3 and 3.4). The activation of G protein coupled receptor by ligand results in the liberation of G alpha and G beta gamma subunits. Gbeta gamma subunits interact and activate GIRK channels.

Additional Information
Compartment plasma membrane , cytosol , extracellular region