Reactome: A Curated Pathway Database
The EBI data centre will be shutting down from the afternoon (BST) of Friday 26th August until the afternoon of Tuesday 30th August 2016 for essential maintenance. This might have an impact on some Reactome services and we apologize for any inconvenience.

Inwardly rectifying K+ channels

Stable Identifier
Homo sapiens
Locations in the PathwayBrowser

Inwardly rectifying K+ channels (Kir channels) show an inward rather than outward (like the voltage gated K+ channels) flow of K+ thereby contributing to maintenance of resting membrane potential and regulation of action potential in excitable tissue. Kir channels are found in a variety of cell types such as cardiac myocytes, neurons, blood cells, osteoblasts, glial cells, epithelial cells, and oocytes. Kir channels can be functionally divided into ATP sensitive K+ channels (Kir 6.1 and Kir 6.2), classical kir channels (Kir 2.1, 2.2, 2.3, 2.4, 5.1) G protein gated K+ channels (Kir 3.1, 3.2, 3.3, 3.4) and K+ transport channels (Kir1.1, 7.1, 4.2, 4.1).

Literature References
Participant Of
Orthologous Events