Reactome: A Curated Pathway Database

Potassium transport channels (R-HSA-1296067)

Species Homo sapiens


Inwardly rectifying potassium transport are tetrameric channels that are found in kidney in the nephron. Kir 1.1 works as a homotetramer, however, Kir 4.1 and 5.1 work as heterotetramers. These channels transport K+ from cytosol to the lumen of the tubules.

Locations in the PathwayBrowser
Additional Information
Compartment plasma membrane , cytosol , extracellular region
Literature References
pubMedId Title Journal Year
19221509 The Kir channel immunoglobulin domain is essential for Kir1.1 (ROMK) thermodynamic stability, trafficking and gating Channels (Austin) 2009