Reactome: A Curated Pathway Database

Activation of voltage gated Potassium channels (R-HSA-1296127) [Homo sapiens]


Activation of voltage gated potassium channel is triggered by membrane potential changes that is sensed by the channel assembly. Activation of voltage-gated potassium channel leads to selective outward current of K+ ions.

Additional Information
Compartment plasma membrane , cytosol , extracellular region
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
Octamer of Voltage gated K+ channels voltage-gated potassium channel activity (0005249)  
Literature References
pubMedId Title Journal Year
21231794 Inhibition of the heterotetrameric K+ channel KCNQ1/KCNE1 by the AMP-activated protein kinase Mol Membr Biol 2011
20393197 Ancillary subunits associated with voltage-dependent K+ channels Physiol Rev 2010