Reactome: A Curated Pathway Database

Activation of voltage gated Potassium channels

Stable Identifier
R-HSA-1296127
Type
Reaction
Species
Homo sapiens
Compartment
cytosol, extracellular region, plasma membrane
Locations in the PathwayBrowser
Summation

Activation of voltage gated potassium channel is triggered by membrane potential changes that is sensed by the channel assembly. Activation of voltage-gated potassium channel leads to selective outward current of K+ ions.

Literature References
PubMed ID Title Journal Year
20393197 Ancillary subunits associated with voltage-dependent K+ channels Physiol Rev 2010
21231794 Inhibition of the heterotetrameric K+ channel KCNQ1/KCNE1 by the AMP-activated protein kinase Mol Membr Biol 2011
Participants
input
output
Participant Of
hasEvent
This entity is regulated by:
Title Physical Entity Activity
voltage-gated potassium channel activity of Octamer of Voltage gated K+ channels [plasma membrane] Octamer of Voltage gated K+ channels [plasma membrane] voltage-gated potassium channel activity (0005249)
Orthologous Events
 
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