Reactome: A Curated Pathway Database

GRB7 events in ERBB2 signaling (R-HSA-1306955) [Homo sapiens]


Heterodimers of ERBB2 and ERBB3 are able to bind GRB7 (Fiddes et al. 1998) through phosphorylated tyrosine residues in the C-tail of ERBB3 (Y1199 and Y1262), but the exact downstream signaling of this complex has not been elucidated.

Cross References
Database Identifier
BioModels Database BIOMD0000000175, BIOMD0000000424, BIOMD0000000255