Reactome: A Curated Pathway Database

GRB7 events in ERBB2 signaling (R-HSA-1306955)

Species Homo sapiens


Heterodimers of ERBB2 and ERBB3 are able to bind GRB7 (Fiddes et al. 1998) through phosphorylated tyrosine residues in the C-tail of ERBB3 (Y1199 and Y1262), but the exact downstream signaling of this complex has not been elucidated.

Locations in the PathwayBrowser
Cross References
Database Identifier
BioModels Database BIOMD0000000175, BIOMD0000000424, BIOMD0000000255