Reactome: A Curated Pathway Database
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GRB7 events in ERBB2 signaling

Stable Identifier
R-HSA-1306955
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Heterodimers of ERBB2 and ERBB3 are able to bind GRB7 (Fiddes et al. 1998) through phosphorylated tyrosine residues in the C-tail of ERBB3 (Y1199 and Y1262), but the exact downstream signaling of this complex has not been elucidated.

Participants
Participant Of
Orthologous Events
Cross References