Reactome: A Curated Pathway Database

RORA activates gene expression

Stable Identifier
R-HSA-1368082
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

As inferred from mouse, RORA binds ROR elements (ROREs) in DNA and recruits the coactivators PPARGC1A (PGC-1alpha) and p300 (EP300, a histone acetylase) to activate transcription.

Literature References
Participants
Participant Of
hasEvent
Inferred From
Orthologous Events