Reactome: A Curated Pathway Database
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ABCAs mediate lipid efflux

Stable Identifier
R-HSA-1369028
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The exact roles of ABCA2 (Vulevic et al. 2001, Kaminski et al. 2001), ABCA6 (Kaminski & Wenzel et al. 2001), ABCA9 (Piehler et al. 2002) and ABCA10 (Wenzel et al. 2003), candidates for ABC lipid transporter-related activities, need to be elucidated. Even thought cholesterol-responsiveness has been noted in experimental systems, contribution of these proteins in regulation or in active transport is not yet clear.

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
lipid transporter activity of ABCA cholesterol transporters [plasma membrane] ABCA cholesterol transporters [plasma membrane] lipid transporter activity (0005319)
Orthologous Events