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ABCAs mediate lipid influx

Stable Identifier
R-HSA-1369052
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The exact roles of ABCA2 (Vulevic et al. 2001, Kaminski et al. 2001), ABCA6 (Kaminski & Wenzel et al. 2001), ABCA9 (Piehler et al. 2002) and ABCA10 (Wenzel et al. 2003), candidates for ABC lipid transporter-related activities, need to be elucidated. Even thought cholesterol-responsiveness has been noted in experimental systems, contribution of these proteins in regulation or in active transport is not yet clear.

Participants
Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
lipid transporter activity of ABCA cholesterol transporters [plasma membrane]
Physical Entity
Activity
Orthologous Events