Reactome: A Curated Pathway Database

ABCAs mediate lipid influx (R-HSA-1369052)

Species Homo sapiens

Summation

The exact roles of ABCA2 (Vulevic et al. 2001, Kaminski et al. 2001), ABCA6 (Kaminski & Wenzel et al. 2001), ABCA9 (Piehler et al. 2002) and ABCA10 (Wenzel et al. 2003), candidates for ABC lipid transporter-related activities, need to be elucidated. Even thought cholesterol-responsiveness has been noted in experimental systems, contribution of these proteins in regulation or in active transport is not yet clear.

Locations in the PathwayBrowser
Additional Information
Compartment plasma membrane
Reverse Reaction ABCAs mediate lipid efflux
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
ABCA cholesterol transporters lipid transporter activity (0005319)
Cross References
Database Identifier
Rhea 39749, 39748