Reactome: A Curated Pathway Database

prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) (R-HSA-140664)

Species Homo sapiens

Additional Information
Compartment extracellular region , plasma membrane
Catalyst Activity
PhysicalEntity Activity Active Units
Va:Xa complex (prothrombinase) serine-type endopeptidase activity (0004252)
Literature References
pubMedId Title Journal Year
3052293 Cofactor proteins in the assembly and expression of blood clotting enzyme complexes Annu Rev Biochem 1988
14982929 The factor V activation paradox J Biol Chem 2004