Reactome: A Curated Pathway Database

prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst)

Stable Identifier
R-HSA-140664
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The membrane-bound Va:Xa (prothrombinase) complex rapidly activates large amounts of thrombin.

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
serine-type endopeptidase activity of Va:Xa complex (prothrombinase) [plasma membrane] Va:Xa complex (prothrombinase) [plasma membrane] serine-type endopeptidase activity (0004252)
Orthologous Events