Reactome: A Curated Pathway Database

factor V -> factor Va + factor V activation peptide (R-HSA-140696)

Species Homo sapiens


Activated thrombin (factor IIa) catalyzes the conversion of factor V to factor Va (activated factor V). The activation peptide released in this reaction has no known function.

Locations in the PathwayBrowser
Additional Information
Compartment extracellular region
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
activated thrombin (factor IIa) serine-type endopeptidase activity (0004252)
Literature References
pubMedId Title Journal Year
14982929 The factor V activation paradox J Biol Chem 2004