Reactome: A Curated Pathway Database

factor V -> factor Va + factor V activation peptide

Stable Identifier
R-HSA-140696
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Activated thrombin (factor IIa) catalyzes the conversion of factor V to factor Va (activated factor V). The activation peptide released in this reaction has no known function.

Literature References
PubMed ID Title Journal Year
14982929 The factor V activation paradox J Biol Chem 2004
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
serine-type endopeptidase activity of activated thrombin (factor IIa) [extracellular region] activated thrombin (factor IIa) [extracellular region] serine-type endopeptidase activity (0004252)
Orthologous Events