Reactome: A Curated Pathway Database

fibrin multimer -> fibrin multimer, crosslinked + NH4+

Stable Identifier
R-HSA-140851
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Fibrin multimers are stabilized by the formation of multiple covalent crosslinks between the side chains of specific lysine and glutamine residues in fibrinogen alpha and gamma chains, catalyzed by factor XIIIa.

Literature References
PubMed ID Title Journal Year
The Molecular Genetics of Haemostasis and Its Inherited Disorders The Molecular Genetics of Haemostasis and Its Inherited Disorders 1994
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
protein-glutamine gamma-glutamyltransferase activity of factor XIIIa [extracellular region] factor XIIIa [extracellular region] protein-glutamine gamma-glutamyltransferase activity (0003810)
Orthologous Events