Reactome: A Curated Pathway Database

fibrin multimer -> fibrin multimer, crosslinked + NH4+ (R-HSA-140851)

Species Homo sapiens

Summation

Fibrin multimers are stabilized by the formation of multiple covalent crosslinks between the side chains of specific lysine and glutamine residues in fibrinogen alpha and gamma chains, catalyzed by factor XIIIa.

Locations in the PathwayBrowser
Additional Information
Compartment extracellular region
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
factor XIIIa protein-glutamine gamma-glutamyltransferase activity (0003810)
Literature References
pubMedId Title Journal Year
The Molecular Genetics of Haemostasis and Its Inherited Disorders The Molecular Genetics of Haemostasis and Its Inherited Disorders 1994