Reactome: A Curated Pathway Database

Collagen type II degradation by MMP14 (R-HSA-1474196)

Species Homo sapiens


The membrane-type MMP MMP14 (MT1-MMP) is a fibrillar collagenase. MMP14 is able to degrade collagen types I, II and III (Ohuchi et al. 1997).

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Compartment plasma membrane
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Catalyst Activity
PhysicalEntity Activity Active Units
MMP14 serine-type endopeptidase activity (0004252)