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Collagen type II degradation by MMP14

Stable Identifier
R-HSA-1474196
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The membrane-type MMP MMP14 (MT1-MMP) is a fibrillar collagenase. MMP14 is able to degrade collagen types I, II and III (Ohuchi et al. 1997).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
metalloendopeptidase activity of MMP14,TMPRSS6 [plasma membrane]
Physical Entity
Activity
Inferred From