Reactome: A Curated Pathway Database

Acyl chain remodelling of PE (R-HSA-1482839) [Homo sapiens]


In the acyl chain remodelling pathway (Lands cycle), phosphatidylethanolamine (PE) is hydrolyzed by phopholipases and subsequently reacylated by acyltransferases. These cycles modify the fatty acid composition of glycerophospholipids to generate diverse molecules asymmetrically distributed in the cell membrane (Ghomashchi et al. 2010, Singer et al. 2002, Cao et al. 2008, Zhao et al. 2008, Hishikawa et al. 2008).

Additional Information
GO Biological Process phosphatidylethanolamine acyl-chain remodeling (0036152)