Reactome: A Curated Pathway Database

Cho is phosphorylated to PCho by CHK dimer

Stable Identifier
R-HSA-1483004
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

In the cytosol, choline kinase alpha subunit (CHKA) homodimer, choline kinase beta subunit (CHKB) dimer, or CHKA:CHKB heterodimer phosphorylates choline (Cho) to produce phosphocholine (PCho) (Malito et al. 2006, Gallego-Ortega et al. 2009).

Literature References
Participants
Participant Of
hasEvent
This entity is regulated by:
Title Physical Entity Activity
choline kinase activity of CHK dimer [cytosol] CHK dimer [cytosol] choline kinase activity (0004103)
Orthologous Events