Reactome: A Curated Pathway Database

Cho is phosphorylated to PCho by CHK dimer (R-HSA-1483004) [Homo sapiens]


In the cytosol, choline kinase alpha subunit (CHKA) homodimer, choline kinase beta subunit (CHKB) dimer, or CHKA:CHKB heterodimer phosphorylates choline (Cho) to produce phosphocholine (PCho) (Malito et al. 2006, Gallego-Ortega et al. 2009).

Additional Information
Compartment cytosol
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PhysicalEntity Activity Active Units
CHK dimer choline kinase activity (0004103)