Reactome: A Curated Pathway Database

PA is dephosphorylated to DAG by LPIN (R-HSA-1483203)

Species Homo sapiens


At the endoplasmic reticulum (ER) membrane, phosphatidate phosphatase 1-3 (LPIN) dephosphorylates phosphatidic acid (PA) to form diacylglycerol (DAG) (Grimsey et al. 2008, Donkor et al. 2007).

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Additional Information
Compartment endoplasmic reticulum membrane , cytosol
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Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
LPIN phosphatidate phosphatase activity (0008195)