Reactome: A Curated Pathway Database

Synthesis of PE

Stable Identifier
R-HSA-1483213
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

De novo (Kennedy pathway) synthesis of phosphatidylethanolamine (PE) involves phosphorylation of ethanolamine (ETA) to phosphoethanolamine (PETA) followed by condensing with cytidine triphosphate (CTP) to form CDP-ethanolamine (CDP-ETA). Diacylglycerol (DAG) and CDP-ETA together then form PE. Alternatively, PE is formed when phosphatidylserine (PS) is decarboxylated by phosphatidylserine decarboxylase proenzyme (PISD) (Henneberry et al. 2002, Vance 1991, Vance 1990).

Literature References
Participants
Participant Of
Orthologous Events