Reactome: A Curated Pathway Database

DAG and IP3 signaling (R-HSA-1489509)

Species Homo sapiens


This pathway describes the generation of DAG and IP3 by the PLCgamma-mediated hydrolysis of PIP2 and the subsequent downstream signaling events.

Locations in the PathwayBrowser
Additional Information
Compartment cytosol , extracellular region , plasma membrane
Cross References
Database Identifier
BioModels Database BIOMD0000000088
Literature References
pubMedId Title Journal Year
16260143 Phospholipase C-gamma: diverse roles in receptor-mediated calcium signaling Trends Biochem Sci 2005