Reactome: A Curated Pathway Database

kallikrein + C1Inh -> kallikrein:C1Inh

Stable Identifier
R-HSA-158399
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Activated kallikrein binds to C1Inh (plasma protease C1 inhibitor) (Bock et al. 1986), forming a stable and enzymatically inactive complex. This reaction appears to be the major means by which kallikrein is inactivated (kallikrein can also be inactivated by binding to alpha2-macroglobulin) (Harpel et al. 1985; Ratnoff et al. 1969).

Literature References
Participants
Participant Of
Orthologous Events