Reactome: A Curated Pathway Database
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Furin cleaves pro-protein S to protein S

Stable Identifier
R-HSA-159773
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
pro-protein S -> protein S + protein S propeptide
Locations in the PathwayBrowser
Summation

Furin, associated with the Golgi membrane, cleaves pro-protein S to form mature, gamma-carboxylated protein S (Wasley et al. 1993).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
serine-type endopeptidase activity of FURIN [Golgi membrane] FURIN [Golgi membrane] serine-type endopeptidase activity (0004252)
Orthologous Events