Reactome | OxA-ARSK [endoplasmic reticulum lumen]

OxA-ARSK [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-1614364

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

active ARSK, Arylsulfatase K, ARSK_HUMAN, ARSK

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6UWY0 ARSK

Gene Names

ARSK, TSULF, UNQ630/PRO1246

Chain

signal peptide:1-22, chain:23-536

Reference Genes

BioGPS Gene:153642 ARSK

COSMIC (genes):ARSK ARSK

CTD Gene:153642 ARSK

dbSNP Gene:153642 ARSK

ENSEMBL:ENSG00000164291 ARSK

ENSEMBL_homo_sapiens_GENE:ENSG00000164291.17 ARSK

HGNC:25239 ARSK

KEGG Gene (Homo sapiens):153642 ARSK

Monarch:153642 ARSK

NCBI Gene:153642 ARSK

OMIM:610011 ARSK

UCSC:Q6UWY0 ARSK

Reference Transcript

RefSeq:NM_198150.2 ARSK

Other Identifiers

11740175_a_at

11740176_at

11755623_a_at

153642

16987361

239147_PM_at

239147_at

2820866

2820867

2820870

2820871

2820872

2820876

2820877

2820878

2820879

2820880

2820881

2820882

2820883

54669_at

75161_at

8106962

A_23_P312536

A_33_P3273664

GE87386

GO:0003824

GO:0004065

GO:0005576

GO:0005764

GO:0005773

GO:0005783

GO:0005788

GO:0008484

GO:0015024

GO:0016787

GO:0043226

GO:0046872

HMNXSV003017599

Hs.151380.0.A1_3p_at

ILMN_1657050

TC05000458.hg

Participates

as a member of

active ARS [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

ARSK [endoplasmic reticulum lumen]

Inferred To

arsk [endoplasmic reticulum lumen] (Xenopus tropicalis)

ARSK [endoplasmic reticulum lumen] (Sus scrofa)

OxA-ARSK [endoplasmic reticulum lumen] (Bos taurus)

OxA-ARSK [endoplasmic reticulum lumen] (Canis familiaris)

OxA-ARSK [endoplasmic reticulum lumen] (Danio rerio)

OxA-ARSK [endoplasmic reticulum lumen] (Gallus gallus)

OxA-ARSK [endoplasmic reticulum lumen] (Mus musculus)

OxA-ARSK [endoplasmic reticulum lumen] (Rattus norvegicus)

Modified Residues

Name

L-3-oxoalanine (Ser) at 90

Coordinate

PsiMod Name

L-3-oxoalanine (Ser)

PsiMod Definition

A protein modification that effectively converts an L-serine residue to L-oxoalanine.

Cross References

RefSeq

NP_937793.1

OpenTargets

ENSG00000164291

IntEnz

3.1.6.1

GeneCards

Q6UWY0

HPA

ENSG00000164291-ARSK

Ensembl

ENSP00000369346, ENSG00000164291, ENST00000380009

PRO

Q6UWY0

Pharos - Targets

Q6UWY0

HMDB Protein

HMDBP07461