Reactome: A Curated Pathway Database

Excess cysteine yields lanthionine and H2S (R-HSA-1614591) [Homo sapiens]


Excess homocysteine will change the enzymatic activity of CBS such that other reactions than transsulfuration take place. In these reactions, oxobutanoate, lanthionine, and homolanthionine are produced by cystathionine gamma-lyase (CTH) (Chiku et al. 2009, Steegborn et al. 1999)

Additional Information
Compartment cytosol
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Catalyst Activity
PhysicalEntity Activity Active Units
CTH tetramer:PXLP L-cysteine desulfhydrase activity (0080146)  
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