Reactome: A Curated Pathway Database

CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine

Stable Identifier
R-HSA-1614645
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
Cysteine is oxidized
Locations in the PathwayBrowser
Summation

Oxidation of the thiol moiety of cysteine yields sulfinoalanine, which itself is processed to hypotaurine by an as of yet uncharacterized enzyme in humans . Whether further oxidation of hypotaurine to taurine needs an enzyme is unknown at present (Ye et al. 2007).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
cysteine dioxygenase activity of CDO1:Fe2+ [cytosol] CDO1:Fe2+ [cytosol] cysteine dioxygenase activity (0017172)
Orthologous Events
Cross References
Rhea