Reactome: A Curated Pathway Database

CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine (R-HSA-1614645) [Homo sapiens]


Oxidation of the thiol moiety of cysteine yields sulfinoalanine, which itself is processed to hypotaurine by an as of yet uncharacterized enzyme in humans . Whether further oxidation of hypotaurine to taurine needs an enzyme is unknown at present (Ye et al. 2007).

Additional Information
Compartment cytosol
GO Biological Process L-cysteine catabolic process (0019448)
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
CDO1:Fe2+ cysteine dioxygenase activity (0017172)  
Cross References
Database Identifier
Rhea 20444, 20442, 20441