Reactome: A Curated Pathway Database
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Host Interactions of HIV factors

Stable Identifier
R-HSA-162909
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Like all viruses, HIV-1 must co-opt the host cell macromolecular transport and processing machinery. HIV-1 Vpr and Rev proteins play key roles in this co-optation. Efficient HIV-1 replication likewise requires evasion of APOBEC3G-mediated mutagenesis of reverse transcripts, a process mediated by the viral Vif protein.

Participants
Participant Of
hasEvent
Disease
Diseases
Name Identifier Synonyms