Reactome: A Curated Pathway Database

Host Interactions of HIV factors (R-HSA-162909) [Homo sapiens]


Like all viruses, HIV-1 must co-opt the host cell macromolecular transport and processing machinery. HIV-1 Vpr and Rev proteins play key roles in this co-optation. Efficient HIV-1 replication likewise requires evasion of APOBEC3G-mediated mutagenesis of reverse transcripts, a process mediated by the viral Vif protein.

Name Identifier Synonyms
Human immunodeficiency virus infectious disease 526 [HIV infection]