Reactome: A Curated Pathway Database

Gamma carboxylation, hypusine formation and arylsulfatase activation (R-HSA-163841)

Species Homo sapiens

Summation

After translation, many newly formed proteins undergo further covalent modifications that alter their functional properties and that are essentially irreversible under physiological conditions in the body. These modifications include the vitamin K-dependent attachment of carboxyl groups to glutamate residues and the conversion of a lysine residue in eIF5A to hypusine, and the conversion of a histidine residue in EEF to diphthamide.

Locations in the PathwayBrowser
Additional Information
GO Biological Process post-translational protein modification (0043687)
Inferred Entries
Orthologous events