Reactome: A Curated Pathway Database

MTOR (R-HSA-165662) [Homo sapiens]

Reference Gene Product
Locations in the PathwayBrowser
Other forms of this molecule
Additional Information
External reference name MTOR
External reference id P42345
Compartment cytosol
Other Identifiers
 0003190369  11716133_a_at  11716134_a_at  11750567_a_at  1AUE
 1FAP  1NSG  202288_at  2475  267_at
 2FAP  2GAQ  2NPU  2RSE  3FAP
 40139_at  4DRH  4DRI  4DRJ  4FAP
 4JSN  4JSP  4JSV  4JSX  4JT5
 4JT6  A_23_P34606  AAA58486  AAC39933  AAC41713
 AAI17167  AB209995  AJ300188  AL049653  AL109811
 AL391561  BAE06077  BC117166  CAB005057  CAC15570
 CAI17228  CAI22105  CAI22145  CCDS127  ENSG00000198793
 ENSP00000354558  ENST00000361445  EntrezGene:2475  g3282238_3p_at  GE81461
 HGNC:3942  Hs.338207  ILMN_1769031  IPR000403  IPR003151
 IPR003152  IPR009076  IPR011009  IPR014009  IPR016024
 IPR018936  IPR024585  L34075  L34075_at  L35478
 LRG_734  LRG_734t1  MIM:601231  MTOR  MTOR-001
 NM_004958  NP_004949  OTTHUMP00000001983  PF00454  PF02259
 PF02260  PF08771  PF11865  PH_hs_0016579  R-HSA-109703
 R-HSA-109704  R-HSA-112399  R-HSA-1168372  R-HSA-1227986  R-HSA-1236394
 R-HSA-1250342  R-HSA-1257604  R-HSA-1280218  R-HSA-1433557  R-HSA-162582
 R-HSA-1632852  R-HSA-1643685  R-HSA-165159  R-HSA-166208  R-HSA-166520
 R-HSA-168249  R-HSA-168256  R-HSA-177929  R-HSA-180292  R-HSA-186763
 R-HSA-186797  R-HSA-187037  R-HSA-190236  R-HSA-194138  R-HSA-1963642
 R-HSA-198203  R-HSA-212436  R-HSA-2172127  R-HSA-2219528  R-HSA-2262752
 R-HSA-2404192  R-HSA-2424491  R-HSA-2428924  R-HSA-2428928  R-HSA-2454202
 R-HSA-2730905  R-HSA-3371556  R-HSA-3371571  R-HSA-3700989  R-HSA-380972
 R-HSA-388841  R-HSA-389356  R-HSA-389357  R-HSA-4420097  R-HSA-5218920
 R-HSA-5628897  R-HSA-5654687  R-HSA-5654689  R-HSA-5654695  R-HSA-5654696
 R-HSA-5654708  R-HSA-5654710  R-HSA-5654716  R-HSA-5654720  R-HSA-5654736
 R-HSA-5654738  R-HSA-5654741  R-HSA-5654743  R-HSA-5663202  R-HSA-5674400
 R-HSA-74160  R-HSA-74751  R-HSA-74752  R-HSA-983705  SM00146
 U88966  uc001asd.4  UPI000012ABD3  XM_005263438  XP_005263495
Secondary Identifiers MTOR_HUMAN, Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3
Gene Names MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Chain chain:1-2549
This entry is a component of:
hasComponent
Reference Genes
Database Identifier
dbSNP Gene 2475
CTD Gene 2475
BioGPS Gene 2475
NCBI Gene 2475
ENSEMBL ENSG00000198793
KEGG Gene MTOR
Orphanet 23236
Reference Transcripts
Database Identifier
RefSeq NM_004958
Cross References
Database Identifier
RefSeq NP_004949
ZINC_target P42345
DOCK Blaster 2GAQ, 2NPU, 1AUE, 4JT6, 4JSX, 4JT5, 4JSN, 4JSP, 4JSV, 4DRH, 4DRI, 4DRJ, 4FAP, 2RSE, 3FAP, 2FAP, 1NSG, 1FAP
HMDB_protein HMDBP02611
PRO P42345
GeneCards P42345
UCSC human P42345
Protein Data Bank 2GAQ, 2NPU, 1AUE, 4JT6, 4JSX, 4JT5, 4JSN, 4JSP, 4JSV, 4DRH, 4DRI, 4DRJ, 4FAP, 2RSE, 3FAP, 2FAP, 1NSG, 1FAP
Interactions
Confidence Score Interactor Accession Interactor Name Evidences
0.968 Q8N122 RPTOR 32
0.96 Q6R327 RICTR 27
0.855 Q9BPZ7 SIN1 11
0.688 Q9BVC4 LST8 4
0.675 Q8TCU6 PREX1 11
0.609 P62942 FKB1A 2
0.597 Q9Y4R8 TELO2 3
0.589 Q12933 TRAF2 2
0.576 P62820 RAB1A 4
0.573 P31749 AKT1 2
0.564 Q96B36 AKTS1 2
0.525 Q96EB6 SIR1 2
0.524 Q8TB45 DPTOR 5
0.462 Q9P2J5 SYLC 2
0.462 P61254 RL26 6