Reactome: A Curated Pathway Database

Nucleophillic attack by 3'-hydroxyl oxygen of nascent HIV-1 transcript on the Alpha phosphate of NTP (R-HSA-167130)

Species Homo sapiens


At the beginning of this reaction, 1 molecule of 'HIV-1 initiation complex' is present. At the end of this reaction, 1 molecule of 'HIV-1 initiation complex with phosphodiester-PPi intermediate' is present.

This reaction takes place in the 'nucleus'.

Locations in the PathwayBrowser
Additional Information
Compartment nucleoplasm
Name Identifier Synonyms
Human immunodeficiency virus infectious disease 526 [HIV infection]
Literature References
pubMedId Title Journal Year
9405375 Three transitions in the RNA polymerase II transcription complex during initiation. EMBO J 1998