The capping enzyme interacts with the Spt5 subunit of transcription elongation factor DSIF. This interaction may couple the capping reaction with promoter escape or elongation, thereby acting as a "checkpoint" to assure that capping has occurred before the polymerase proceeds to make the rest of the transcript.
|Human immunodeficiency virus infectious disease||526||[HIV infection]|
|24354960||Cap-binding complex (CBC)||Biochem. J.||2014|